Fig. 2From: Herpetic esophagitis in immunocompentent host: cases reportA) The esophageal biopsy shows intraepithelial inflammatory infiltration and multinuclear cells (“coin stack”-like appearance), with cytoplasm of ground-glass appearance and nuclear inclusions suggestive of herpes simplex virus (HSV) infection (hematoxylin-eosin, × 400). B) Immunohistochemistry technique with positive immunostaining demonstrating intranuclear inclusions (anti-HSV-1 antibody, × 200)Back to article page