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Table 2 The distribution of the 29 most predominant species in different groups

From: Human papillomavirus infection and cervical intraepithelial neoplasia progression are associated with increased vaginal microbiome diversity in a Chinese cohort

  Normal HPV LSIL HSIL Cancer Total
N (%) N (%) N (%) N (%) N (%) N (%)
Lactobacillus crispatus 16 (23.5) 15 (19.2) 14 (27.5) 3 (13.0) 0 (0) 48 (21.0)
Lactobacillus iners 30 (44.1) 21 (27.0) 20 (39.2) 6 (26.1) 1 (11.1) 78 (34.1)
Lactobacillus jensenii 0 (0) 1 (1.3) 0 (0) 1 (4.3) 0 (0) 2 (0.9)
Lactobacillus gasseri 1 (1.5) 1 (1.3) 0 (0) 0 (0) 0 (0) 2 (0.9)
Anaerococcus spp. 1 (1.5) 0 (0) 0 (0) 0 (0) 0 (0) 1 (0.4)
Atopobium unclassified 1 (1.5) 0 (0) 0 (0) 0 (0) 0 (0) 1 (0.4)
Bacillus unclassified 0 (0) 7 (9.0) 5 (9.8) 3 (13.0) 1 (11.1) 16 (7.0)
Bifidobacterium breve 1 (1.5) 0 (0) 1 (2.0) 0 (0) 0 (0) 2 (0.9)
Bifidobacterium unclassified 0 (0) 1 (1.3) 0 (0) 0 (0) 0 (0) 1 (0.4)
Candidatus Mycoplasma 0 (0) 1 (1.3) 0 (0) 0 (0) 0 (0) 1 (0.4)
Comamonadaceae unclassified 0 (0) 0 (0) 0 (0) 0 (0) 1 (11.1) 1 (0.4)
Veillonella montpellierensis 0 (0) 1 (1.3) 0 (0) 0 (0) 0 (0) 1 (0.4)
Escherichia Shigella 0 (0) 3 (3.8) 1 (2.0) 0 (0) 0 (0) 4 (1.7)
Faecalibacterium unclassified 0 (0) 0 (0) 0 (0) 1 (4.3) 0 (0) 1 (0.4)
Finegoldia unclassified 0 (0) 1 (1.3) 0 (0) 0 (0) 0 (0) 1 (0.4)
Fusobacterium mortiferum 0 (0) 0 (0) 0 (0) 0 (0) 1 (11.1) 1 (0.4)
Gardnerella vaginalis 9 (13.2) 10 (12.8) 6 (11.8) 1 (4.3) 0 (0) 26 (11.4)
Megasphaera unclassified 0 (0) 1 (1.3) 0 (0) 1 (4.3) 0 (0) 2 (0.9)
Porphyromonas somerae 1 (1.5) 0 (0) 0 (0) 0 (0) 0 (0) 1 (0.4)
Porphyromonas uenonis 0 (0) 0 (0) 0 (0) 0 (0) 1 (11.1) 1 (0.4)
Prevotella amnii 2 (3.0) 3 (3.8) 0 (0) 1 (4.3) 1 (11.1) 7 (3.1)
Prevotella bivia 1 (1.5) 0 (0) 0 (0) 1 (4.3) 1 (11.1) 3 (1.3)
Prevotella timonensis 1 (1.5) 2 (2.6) 0 (0) 1 (4.3) 0 (0) 4 (1.7)
Prevotella unclassified 1 (1.5) 1 (1.3) 0 (0) 1 (4.3) 0 (0) 3 (1.3)
Ralstonia pickettii 0 (0) 1 (1.3) 0 (0) 0 (0) 0 (0) 1 (0.4)
Shuttleworthia uncultured 1 (1.5) 2 (2.6) 1 (2.0) 2 (8.7) 0 (0) 6 (2.6)
Sneathia amnii 2 (2.9) 3 (3.8) 2 (3.9) 0 (0) 1 (11.1) 8 (3.5)
Sneathia sanguinegens 0 (0) 0 (0) 0 (0) 0 (0) 1 (11.1) 1 (0.4)
Streptococcus unclassified 0 (0) 3 (3.8) 1 (2.0) 1 (4.3) 0 (0) 5 (2.1)