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Table 3 Antibiotic frequencies, appropriateness and compliance

From: The effectiveness of a simple antimicrobial stewardship intervention in general practice in Australia: a pilot study

 

(A)

Number of prescriptions

(B)

Appropriateness of prescriptiona

([B/A (assessable prescriptions)]%)

(C)

Guideline compliancea

([C/A (assessable prescriptions)]%)

Antimicrobial

PRE n(%)

POST n(%)

p value†

PRE n(%)

POST n(%)

p value†

PRE n(%)

POST n(%)

p value†

Amoxicillin

73 (18.5)

71 (19.0)

0.859

63 (86.3)

68 (98.5)

0.007

40 (56.3)

46 (76.6)

0.015

Doxycycline

71 (18.0)

66 (17.7)

0.942

62 (87.3)

63 (98.4)

0.014

40 (57.1)

52 (83.9)

0.001

Cefalexin

49 (12.4)

57 (15.3)

0.244

29 (59.2)

53 (98.1)

< 0.001

16 (34.0)

16 (31.4)

0.784

Amoxicillin/clavulanic acid

35 (8.9)

49 (13.1)

0.062

24 (68.6)

34 (72.3)

0.716

12 (36.4)

15 (35.7)

0.949

Trimethoprim

30 (7.6)

26 (7.0)

0.709

28 (93.3)

26 (100)

0.179

9 (31.0)

14 (60.9)

0.031

Roxithromycin

21 (5.3)

4 (1.1)

0.001

9 (42.9)

2 (50.0)

0.793

0 (0.0)

1 (33.3)

0.007

Erythromycin

15 (3.8)

7 (1.9)

0.115

9 (60.0)

5 (71.4)

0.605

1 (7.1)

0 (0.0)

0.004

Phenoxymethylpenicillin

14 (3.5)

8 (2.1)

0.241

13 (92.7)

6 (75.0)

0.246

11 (84.6)

2 (33.3)

0.025

Metronidazole

13 (3.3)

27 (7.2)

0.015

6 (46.2)

26 (96.3)

0.001

1 (9.1)

6 (18.7)

0.509

Cefaclor

12 (3.0)

6 (1.6)

0.198

2 (16.7)

3 (60.0)

0.074

1 (8.3)

0 (0.0)

0.468

Flucloxacillin

12 (3.0)

10 (2.7)

0.803

11 (91.7)

10 (100.0)

0.351

8 (72.7)

7 (70.0)

0.891

Azithromycin

11 (2.8)

4 (1.1)

0.091

4 (36.4)

4 (100.0)

0.029

3 (27.3)

2 (50.0)

0.410

  1. Other (39 prescriptions, 38 prescriptions): norfloxacin, tinidazole, nitrofurantoin, ciprofloxacin, clindamycin, cefuroxime, fluconazole, ivermectin, minocycline, methenamine hippurate, clarithromycin, trimethoprim/sulfamethoxazole, dicloxacillin
  2. aSome missing data ranging from 1 to 15 prescriptions. Percentages calculated based on assessable prescriptions
  3. †p value for comparison of proportions between cohorts