Table 2 Factors associated with estimated glomerular filtration rate at baseline in univariate and multivariate linear regression in 340 antiretroviral naïve HIV positive adults in Ethiopia. Values are coefficient B, 95% confidence interval (CI) and P value

< 0.001

 18–25

–

 26–35

−11.1 (−16.2; − 5.89)

< 0.001

−11.6 (−17.0; −6.3)

< 0.001

 36–45

−24.0 (−30.1; − 17.92)

< 0.001

−25.1(−31.6; − 18.7)

< 0.001

  > 45

−33.9 (− 41.8; − 25.93)

< 0.001

−35.5 (− 43.9; − 27.1)

< 0.001

 Sex, Female

5.1 (0.3; 9.8)

0.04

−4.6 (− 9.6; 0.4)

0.07

 I

–

–

–

–

 II

0.1 (−5.8; 6.0)

0.98

–

–

 III

1.4 (−4.3; 7.2)

0.62

–

–

 IV

− 1.7 (− 10.7; 7.1)

0.69

–

–

 Weight, kg

−0.3 (− 0.5; 0.01)

0.06

− 0.2 (− 0.5; 0.1)

0.17

 Fat Free mass, Kg

− 0.2 (− 0.5; 0.2)

0.32

–

–

 Fat mass, kg

− 0.3 (− 0.8; 0.1)

0.15

–

–

 Height, m

− 0.2 (− 0.5; 0.06)

0.13

–

–

 Body mass index, kg/m²

− 0.4 (− 1.2; 0.5)

0.42

–

–

 Fat mass index, kg/m²

− 0.5 (− 1.6; 0.6)

0.34

–

–

 Fat free mass index, kg/m²

− 0.03 (−1.4; 1.4)

0.96

–

–

 Hypertension, Yes

−15.7 (−32.8; 1.3)

0.07

−6.6 (−22.0; 8.7)

0.39

 C-reactive protein, mg/L

−0.1 (− 0.2; 0.01)

0.08

− 0.1 (− 0.2; − 0.02)

0.02

 CD4 count, cells/ul

−0.002 (− 0.02; 0.02)

0.88

–

–

 On tuberculosis treatment, Yes

6.1 (−1.3; 13.5)

0.11

–

–

 Hepatitis B surface antigen positive¹, Yes

1.8 (−10.0; 13.7)

0.76

–

–

 Hepatitis C virus antibody Positive², Yes

18.8 (−10.8; 48.3)

0.21

–

–

 Viral load, log (copies+ 1/mL)

0.8 (−1.4; 3.2)

0.45

–

–