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Table 3 Predictive values of independent risk factors and established models containing different risk factors for in-hospital mortality of patients with age ≥ 60 years

From: Predictive risk score model for severe fever with thrombocytopenia syndrome mortality based on qSOFA and SIRS scoring system

Parameters

OR (95% CI)

P value

Cutoff value

AUC (95% CI)

SEN

SPE

PPV

NPV

LR+

LR-

Age (years)

1.135 (1.037–1.243)

0.006

> 72

0.706 (0.640–0.767)

56.2

74.5

53.9

76.1

2.2

0.59

> 74

46.6

81.8

57.6

74.2

2.55

0.65

lactate (mmol/L)

2.592 (1.06–6.34)

0.037

> 1.17

0.757 (0.674–0.828)

85.5

52

56.6

83

1.78

0.28

> 2.1

38.2

94.7

84

67.6

7.16

0.65

Hs-CRP (mmol/L)

1.058 (1.007–1.11)

0.024

> 6.3

0.729 (0.69–0.789)

81.7

54.7

48.3

85.2

1.81

0.33

> 3.14

25.4

95.6

75

71.2

5.79

0.78

AST (U/L)

1.002 (1.000–1.003)

0.01

> 203

0.779 (0.717–0.834)

78.8

66.4

54.9

85.8

2.35

0.32

> 722

39.4

95.6

82.4

75.3

9

0.63

qSOFA

2.364 (1.142–4.89)

0.02

> 0

0.818 (0.759–0.867)

83.6

71.5

61

89.1

2.94

0.23

> 1

39.7

97.1

87.9

75.1

13.6

0.62

SIRS

2.377 (1.025–2.581)

0.008

> 1

0.778 (0.716–0.833)

68.5

76.6

61

82

2.93

0.41

> 2

35.6

94.9

78

73.4

6.97

0.68

M1

3.144 (2.319–4.263)

< 0.0001

> 10.272

0.909 (0.862–0.944)

72.6

94.2

86.9

86.6

12.43

0.29

M2

3.508 (2.506–4.910)

< 0.0001

> 8.544

0.886 (0.835–0.926)

87.7

75.5

64.6

91.9

3.43

0.17

> 9.942

58.9

97.8

26.9

0.42

26.9

0.42

M3

3.11 (2.286–4.231)

< 0.0001

> 9.3

0.883 (0.831–0.923)

73.97

89.78

79.4

86.6

7.24

0.29

M4

3.533 (2.494–5.005)

< 0.0001

> 8.64

0.885 (0.801–0.900)

69.86

89.78

78.5

84.8

6.84

0.34

M5

2.508 (1.951–3.223)

< 0.0001

> 13.68

0.924 (0.879–0.956)

82.2

87.6

77.9

90.2

6.62

0.2

  1. OR odd ratio, CI confidence interval, AUC area under ROC curve, AST aspartate aminotransferase, hs-CRP high-sensitivity C-reactive protein, qSOFA quick sequential organ failure assessment, SIRS systemic inflammatory response syndrome, SEN sensitivity, SPE specificity, PPV positive predictive value, NPV negative predictive value, LR+ positive likelihood ratio, LR- negative likelihood ratio