Table 3 Univariate analysis of mortality risk factors in patients in the intensive care unit with fungal bloodstream infections
Variable | Survival (n = 52) | Death (n = 29) | χ2/F | P |
|---|---|---|---|---|
Sex, male/female (n) | 32/20 | 18/11 | 0.002 | 0.962 |
Age (years; mean ± s.d.) | 56.9 ± 10.4 | 65.7 ± 11.8 | 10.619 | 0.001 |
Disease factors | ||||
Diabetes (n) | 10 | 12 | 4.616 | 0.032 |
Malignant tumor (n) | 3 | 4 | 1.518 | 0.218 |
Cardiovascular disease (n) | 8 | 16 | 14.135 | 0.000 |
Chronic obstructive pulmonary disease (COPD) (n) | 5 | 4 | 0.329 | 0.566 |
Digestive tract disease (n) | 5 | 4 | 0.329 | 0.566 |
Urinary system disease (n) | 8 | 6 | 0.366 | 0.545 |
Hypertension (n) | 13 | 13 | 3.358 | 0.067 |
Serum albumin (g/L) | 39.5 ± 8.6 | 33.1 ± 10.7 | 7.91 | 0.005 |
Serum urea nitrogen (μmol/L) | 19.1 ± 27 | 30.7 ± 53.2 | 1.693 | 0.193 |
γ-gamma glutamyl peptidase (U/L) | 36.2 ± 24.7 | 63.8 ± 67.6 | 6.629 | 0.010 |
Acute Physiology and Chronic Health Evaluation (APACHE) II score | 16.32 ± 1.74 | 19.97 ± 2.90 | 31.565 | 0.000 |
Merger of three or more underlying diseases (n) | 6 | 12 | 7.82 | 0.005 |
Invasive operative factors | ||||
Tracheal intubation (n) | 16 | 13 | 1.601 | 0.206 |
Multi cavity catheter (n) | 11 | 11 | 2.649 | 0.104 |
Central venous catheterization (n) | 23 | 16 | 0.893 | 0.345 |
Catheter retention time (d) | 12.0 ± 4.0 | 14.6 ± 5.8 | 5.070 | 0.024 |
Therapeutic factors | ||||
Hospitalization time in ICU (d) | 9.7 ± 3.8 | 12.1 ± 6.7 | 4.401 | 0.036 |
Gastrointestinal nutrition (n) | 21 | 14 | 0.472 | 0.492 |
Emergency tube (n) | 18 | 14 | 1.454 | 0.228 |
Blood transfusion (n) | 17 | 12 | 0.611 | 0.434 |
Central venous catheter(n) | 33 | 20 | 0.249 | 0.804 |
Patients in shock receiving cathecholamines etc. (n) | 20 | 15 | 1.334 | 0.350 |
Combined use of antibiotics (n) | 25 | 18 | 1.464 | 0.254 |