Table 4 Prediction models for clinical outcome in patients with cryptococcal meningitis
Items | Model 1 (week 0) | Model 2 (week 0-week 10) |
|---|---|---|
Sensitivity | 0.8828571 | 0.9035714 |
Specificity | 0.6950000 | 0.7100000 |
Positive prediction value | 0.8410332 | 0.8505685 |
Negative prediction value | 0.7917769 | 0.8306219 |
Accuracy | 0.81454545 | 0.83318182 |
AUC | 0.8832813 | 0.8985045 |
The importance of variables to the predictive model | ||
Treatment (no treatment) | 98.00 | 97.7358 |
Positive CSF ink stain | 91.491 | 92.6038 |
Age | 89.6036 | 88.6226 |
Charlson index | 85.5472 | 80.8676 |
Treatment (monotherapy) | 81.434 | 86.0568 |
Treatment (triple therapy) | 79.3774 | 81.1326 |
Hemoglobin | 76.1708 | 76.982 |
Negative CSF fungal culture | 72.9062 | 73.5666 |
Neutrophile | 68.3962 | 60.7552 |
CSF proteins | 67.6798 | 57.0194 |
White blood cell | 67.4152 | 49.2082 |
Male | 64.245 | 58.2074 |
CSF WCC | ||
week 0 | 92.3776 | 91.472 |
Week 1 | NA | 15.6604 |
Week 2 | NA | 21.1326 |
Week 3 | NA | 10.2644 |
Week 4 | NA | 7.2828 |
Week 5 | NA | 17.17 |
Week 6 | NA | 14.1516 |
Week 7 | NA | 5.4718 |
Week 8 | NA | 3.7928 |
Week 10 | NA | 22.095 |