From: An unusual Staphylococcus saccharolyticus spondylodiscitis post kyphoplasty: a case report
Year (ref) | Location | Age/Sex | Diagnosis | Risk factors | Comment on clinical presentation | Biology | Microbiological diagnosis | Antimicrobial susceptibility | Final treatment (total duration) | Outcome |
---|---|---|---|---|---|---|---|---|---|---|
1990 [4] | USA | 61/M | Endocarditis | No predisposing valvular heart disease | Low grade fever at onset; moderate-sized mitral valve vegetation | Anemia; thrombocytosis; ESR elevation | BC; all bottles positive at day 10 | Susceptible to PE, OX, VA, GE, CI, CL; resistant to ME | NAF + GE (6 wks) | Favorable at day 30 |
1996 [9] | USA | 57/W | Prosthetic mitral valve endocarditis | NA | Fever; large masses at prosthetic valve level | Anemia; hyperleukocytosis | BC; all anaerobic vials positive at day 1; aerobic vials positive at day 11 | Susceptible to VA, CL, CH; resistant to all β-lactamin agents (including OX, CES, ME, TET) | Valve change; medical treatment (NA) | Died at day 32 of hospitalization |
2009 [10] | USA | NA | Prosthetic valve endocarditis | NA | NA | NA | Mitral valve; anaerobic culture; at day NA | NA | NA | NA |
1990 [11] | China | 21/M | Pneumonia | NA | Blood-stained sputum; multiple spherical focal lesions in the lung (CT scan) | Anemia; hyperleukocytosis | NA | Susceptible to LE, MO; NA for other antibiotics | AZ (6 d); TI + PE (3 d); IM + TI (1 d) | Died at day 120 of hospitalization |
2015 [12] | China | 26/W | Bone marrow infection | NA | High-grade fever; headache at onset; lymph nodes | Anemia; hyperleukocytosis; ESR and CRP strong elevation | Lung biopsy; positive anaerobic culture at day 10? | Susceptible to VA, LE, PE, CL; resistant to ME; | PE + VA (2 d); IM + VA (NA) | Died at day 114 |
2005 [2] | France | 58/M | Spondylodiscitis | No endocarditis; no underlying disease but poor oral hygiene | Thoracic posterior pains for 2 months; fever; weight loss; NSAIDs/corticosteroids treatment | At admission, hyperleukocytosis; ESR and CRP elevation | BC and bone marrow; positive anaerobic cultures at day 3 | Susceptible to VA, TEI, RI, ER, PR, TET, OF, CL; Resistant to ME; No β-lactamase production; no mecA gene | OF+CL (12 wks) | Favorable at year 1 |
2009 [3] | USA | 38/M | Spondylodiscitis | NA | Radicular symptoms treated unsuccessfully by microdiscectomy | Elevation of inflammatory parameters | Negative aerobic cultures; negative acid-fast bacilli | NA | NA | NA |
2017 [5] | NZ | 48/M | Pyomyositis, spermatic cord infection | Type II diabetes; hyperlipidemia | Fever | Neutrophilia; CRP large increase; CPK normal | Multiple muscle biopsies; anaerobic positive culture at 24 h; coinfection S. capitis and S. saccharolyticus | Susceptible to FL; Resistant to PE | CEFA (1 wk); CEP (2 wks) | Favorable at 4 weeks |
2017 (our case) | France | 57/M | Spondylodiscitis | Heavy smoking; alcoholism; unhealthy underweight | Vertebral fractures (treated by kyphoplasty and zygapophyseal joint steroid injection); no fever; unremarkable clinical examination | Hyperleukocytosis; CRP moderate increase | Aerobic cultures negative at day 7 | Susceptible to PE; CEF, MA, RI, TET, FO, OF; no β-lactamase production | AM (4 wks) | Favorable at 46 months |