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Table 3 Estimated excess AIDS/death in the first year after HIV-diagnosis by country and region 2010–2016

From: Estimating the burden of HIV late presentation and its attributable morbidity and mortality across Europe 2010–2016

    Non-late presenters Late presenters Difference LP versus non-LP
Country Number included from COHERE/EuroSIDA Mean follow-up in COHERE/EuroSIDA in the first 12 months following
HIV-diagnosis
1-year incidence of AIDS/deaths observed in COHERE/EuroSIDAa 1-year incidence of AIDS/deaths observed in COHERE/EuroSIDAa Adjusted ratio of 1-year incidence of AIDS/deaths between LP and non-LPb Estimated excess AIDS/deaths attributable to LP (difference LP – non-LP)d 2010–2016
  n mean PYFU IR/1000 PYFU (95%CI) IR/1000 PYFU (95%CI) aIRR (95%CI) n (95% CI)
Austria 920 0.89 4.7 (0.6–17.0) 63.3 (38.5–88.1) 10.20 (2.4–43.3) 44 (7–415)
Belarusc 94 0.98 4.2 (3.2–5.2) 37.7 (4.6–136.1) 9.3 (7.2–11.9) 169 (127–2754)
Belgium 747 0.84 2.8 (0.1–15.4) 79.4 (45.4–113.3) 25.4 (3.4–190.9) 250 (24–1152)
Denmark 635 0.83 7.9 (1.0–28.5) 61.8 (36.9–98.9) 4.2 (0.9–18.4) 17 (0–533)
Estoniac 65 0.98 4.2 (3.2–5.2) 86.6 (10.5–312.7) 9.3 (7.2–11.9) 47 (35–1768)
France 4531 0.68 2.5 (0.7–6.5) 59.8 (47.4–72.2) 19.2 (7.0–52.7) 661 (218–2581)
Germany 3774 0.83 4.4 (1.6–9.6) 58.6 (47.3–69.9) 11.1 (4.8–25.4) 353 (134–2408)
Greece 1829 0.82 5.0 (1.4–12.8) 43.0 (27.6–58.5) 7.5 (2.6–21.5) 82 (20–724)
Italy 6241 0.80 5.1 (2.5–8.8) 44.8 (36.7–53.0) 6.6 (3.6–11.9) 286 (134–2674)
The Netherlands 4680 0.84 5.4 (2.8–9.5) 69.8 (57.4–82.1) 9.9 (5.4–18.0) 163 (81–1490)
Polandc 179 0.99 4.2 (3.2–5.2) 8.8 (0.2–48.9) 9.3 (7.2–11.9) 102 (77–591)
Russiac 168 0.98 4.2 (3.2–5.2) 40.7 (8.4–118.9) 9.3 (7.2–11.9) 10,357 (7768-147,448)
Spain 7118 0.78 1.9 (0.7–4.2) 52.9 (43.8–62.0) 18.9 (8.3–43.2) 404 (165–1377)
Sweden 1830 0.81 7.9 (2.6–18.5) 32.7 (20.6–44.9) 3.7 (1.4–9.7) 24 (4–382)
Switzerland 998 0.82 5.4 (0.7–19.3) 25.0 (12.5–44.6) 5.2 (1.0–25.7) 34 (0–355)
United Kingdom 5208 0.72 5.4 (2.7–9.7) 37.6 (28.4–46.9) 5.1 (2.7–9.9) 382 (153–4252)
Ukrainec 187 0.98 4.2 (3.2–5.2) 59.2 (16.1–151.6) 9.3 (7.2–11.9) 2424 (1818-44,080)
Regione
Centralc 179 0.99 4.3 (3.3–5.4) 8.8 (0.2–48.9) 9.3 (7.2–11.9) 407 (306–2355)
Eastc 327 0.98 4.3 (3.3–5.4) 36.2 (18.7–63.2) 9.3 (7.2–11.9) 14,597 (10,947-109,680)
West 38,511 0.79 4.3 (3.3–5.4) 51.5 (47.9–55.2) 9.2 (7.2–11.9) 3030 (2273-19,934)
  1. aEstimated number of events among LP or non-LP was estimated by applying event rates from COHERE/EuroSIDA to the total number diagnosed HIV-positive in the whole country (incidence rate (PYFU) x mean follow-up (PYFU) x number of LP or non-LP in the whole country). bAdjusted for age, sex and HIV exposure group. cIn Belarus, Estonia, Poland, Russia and Ukraine there were no registered events among non-LP in EuroSIDA/COHERE. The IR and the aIRR given for these countries are the averages for all countries combined. dExcess events were estimated as clinical events in LP compared to non-LP. eAs defined by ECDC. Regional estimates are not summations of those estimated for each country. aIRR Adjusted Incidence Rate Ratio, CI Confidence interval, IR Incidence Rate, LP Late Presentation, PYFU Person years of follow-up
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