Table 3 Association between demographic and clinical factors with drug resistance

Variable

Level

Pan-susceptible, n = 59 (%)

Resistant, n = 11 (%)

P-value

Pan-susceptible, n = 59 (%)

Resistant, n = 8 (%)

P-value

Sex

Female

24 (41%)

4 (36%)

0.789

24 (41%)

2 (25%)

0.393

Male

35 (59%)

7 (64%)

35 (59%)

6 (75%)

Age groups

Adults

(> 17 y)

55 (93%)

10 (91%)

0.785

55 (93%)

7 (88%)

0.563

Children

= < 16 y

4 (7%)

1 (9%)

4 (7%)

1 (12%)

TB/DOTS Facilities

Folang

1 (2%)

0

0.958

1 (2%)

0

0.856

Kalafong

21 (36%)

5 (45%)

21 (36%)

4 (50%)

Mamelodi

9 (15%)

1 (9%)

9 (15%)

0

Potchefstroom

4 (7%)

0

4 (7%)

0

Pretoria West

3 (5%)

1 (9%)

3 (5%)

1 (12%)

Skinner

2 (3%)

0

2 (3%)

0

Steve Biko

11 (19%)

3 (27%)

11 (19%)

2 (50)

Tshwane District Hosp.

8 (14%)

1 (9%)

8 (14%)

1 (13%)

Genotypes

Beijing

22 (37%)

3 (27%)

0.737

22 (37%)

1 (12%)

0.350

Cas_KILI

4 (7%)

0

4 (7%)

0

EAI1_SOM

1 (2%)

1 (9%)

1 (2%)

1 (12%)

LAM11_ZWE

2 (3%)

0

2 (3%)

0

LAM3

4 (7%)

0

4 (7%)

0

LAM4

2 (3%)

1 (9%)

2 (3%)

1 (12%)

LAM9

2 (3%)

1 (9%)

2 (3%)

1 (12%)

S

3 (5%)

0

3 (5%)

0

T1

3 (5%)

0

3 (5%)

0

X1

4 (7%)

1 (9%)

4 (7%)

0

X3

2 (3%)

1 (9%)

2 (3%)

1 (12%)

Unclustered

Orphan/X2

10 (17%

3 (27%)

0.419

10 (17%)

3 (38%)

0.168

Disease Site

Disseminated

4 (7%)

0

0.134

4 (7%)

0

0.036

Lymph nodes

16 (27%)

4 (36%)

16 (27%)

4 (38%)

Meninges

4 (7%)

1 (9%)

4 (7%)

0

EPTB/PTB

3 (5%)

0

3 (5%)

0

Pericardium

1 (2%)

0

1 (2%)

0

Peritoneum

5 (8%)

0

5 (8%)

0

Pleura

19 (32%)

1 (9%)

19 (32%)

0

Genitourinary

2 (3%)

0

2 (3%)

0

Cutaneous TB

5 (8%)

5 (45%)

5 (8%)

5 (63%)