Occurrence of septuple and elevated Pfdhfr-Pfdhps quintuple mutations in a general population threatens the use of sulfadoxine-pyrimethamine for malaria prevention during pregnancy in eastern-coast of Tanzania

Table 2 Combined Pfdhfr-Pfdhps haplotypes

No. of *Pfdhps- Pfdhfr* mutations (haplotype where applicable)	Frequency (n)	Percentage (%)
Wild type (SAKAA-NCSI)	4	0.9
Single (1)^a	0	0
Double (2)^a	11	2.5
Triple (3)^a	30	6.7
Quadruple (4)^a	73	16.3
Quintuple (5) (SGEAA-IRNI)	319	71.4
Sextuple (6)^a	9	2.0
Septuple (7) (AGKGS-IRNI)	1	0.2
Total	447	100

^aThe haplotype(s) type were not indicated if the mutation category had multiple haplotypes

ISSN: 1471-2334