Table 2 Radiographic and laboratory findings of 276 patients with COVID-19 on admission to hospitala
Variable | All Patients | Disease Severity | p value | |
|---|---|---|---|---|
(N = 276) | Non-severe (N = 262) | Severe (N = 14) | ||
Abnormalities on chest CT — no./total no. (%) | 264/276 (95.7%) | 250/262 (95.4%) | 14/14 (100.0%) | 0.53 |
 Ground-glass opacity | 221/276 (80.1%) | 209/262 (79.8%) | 12/14 (85.7%) | 0.45 |
 Local patchy shadowing | 17/276 (6.4%) | 17/262 (6.5%) | 0 | 0.40 |
 Bilateral patchy shadowing | 232/276 (84.1%) | 220/262 (84.0%) | 12/14 (85.7%) | 0.41 |
 Interstitial abnormalities | 40/276 (14.5%) | 37/262 (14.1%) | 3/14 (21.4%) | 0.54 |
Laboratory findings | ||||
 White-cell count | ||||
  Median (IQR) — per mm3 | 4700 (3800–6100) | 4700 (3800–6000) | 6000 (4000–7100) | 0.27 |
 Distribution — no./total no. (%) | ||||
   > 10,000 per mm3 | 16/276 (5.8) | 15/262 (5.7) | 1/14 (7.1) | 0.70 |
   < 4000 per mm3 | 83/276 (30.1) | 79/262 (30.2) | 4 /14 (28.6) | 0.67 |
 Lymphocyte count | ||||
  Median (IQR) — per mm3 | 1100 (800–1500) | 1100 (800–1500) | 700 (400–800) | < 0.01 |
 Distribution — no./total no. (%) | ||||
   < 1500 per mm3 | 204/276 (75.0) | 193/262 (73.7) | 11/14 (78.6) | 0.72 |
 Eosinocyte count | ||||
  Median (IQR) — per mm3 | 0.01 (0–0.03 | 0.01 (0–0.03) | 0 (0–0.01) | 0.19 |
 Distribution — no./total no. (%) | ||||
   < 100 per mm3 | 126/276 (45.7) | 117/262 (44.7) | 9/14 (64.3) | 0.33 |
 Platelet count | ||||
  Median (IQR) — per mm3 | 177,000 (140000–221,000) | 177,000 (141000–222,000) | 136,000 (112000–196,000) | 0.03 |
 Distribution — no./total no. (%) | ||||
   < 150,000 per mm3 | 87/276 (31.5) | 80/262 (30.5) | 7/14 (50.0) | < 0.01 |
  Median hemoglobin (IQR) — g/dl | 131.5 (123.0–143.0) | 132.0 (124.0–143.0) | 130.0 (100.0–139.0) | 0.19 |
 Distribution of other findings — no./total no. (%) | ||||
  C-reactive protein ≥10 mg/L | 162/266 (60.9) | 152/252 (60.3) | 10/14 (71.4) | 0.30 |
  Procalcitonin ≥0.5 ng/ml | 6/240 (2.5) | 5/226 (2.2) | 1/14 (7.1) | 0.31 |
  Lactate dehydrogenase ≥250 U/L | 31/93 (33.3) | 27/88 (30.7) | 4/14 (28.6) | 0.57 |
  Aspartate aminotransferase > 40 U/L | 39/274 (14.2) | 34/260 (13.1) | 5/14 (35.7) | 0.03 |
  Alanine aminotransferase > 40 U/L | 61/274 (22.3) | 58/260 (22.3) | 3/14 (21.4) | 0.62 |
  Total bilirubin > 17.1 μmol/L | 43/274 (15.7) | 42/260 (16.2) | 1/14 (7.1) | 0.32 |
  Creatine kinase ≥200 U/L | 9/81 (11.1) | 7/78 (9.0) | 2/3 (66.7) | 0.03 |
  Creatinine ≥115 μmol/L | 6/274 (2.2) | 3/260 (1.2) | 3/14 (21.4) | < 0.01 |
  D-dimer > 0.5 mg/L | 123/229 (53.7) | 115/219 (52.5) | 8/10 (80.0) | 0.08 |
  Myohemoglobin > 80 μg/L | 18/204 (8.0) | 13/191 (6.8) | 5/13 (38.5) | < 0.01 |
  Erythrocyte sedimentation rate > 20 mm/h | 180/201 (90.0) | 169/190 (88.9) | 11/ 11 (100.0) | 0.29 |