Table 1 Clinical characteristics of 276 patients with COVID-19 on admission
Characteristic | All Patients | Disease Severitya | p value | |
|---|---|---|---|---|
(N = 276) | Non-severe (N = 262) | Severe (N = 14) | ||
Age | ||||
 Median (IQR) — yr | 51.0 (41.0–58.0) | 50.0 (39.0–57.0) | 65.0 (60.0–72.8) | < 0.01 |
Distribution — no./total no. (%) | ||||
 0–19 yr | 4/276 (1.4) | 4/262 (1.5) | 0 | 0.50 |
 20–59 yr | 212/276 (76.8) | 209/262 (79.8) | 3/14 (21.4) | < 0.01 |
  > 60 yr | 60/276 (21.7) | 49/262 (18.7) | 11/14 (78.6) | < 0.01 |
 Male sex-no./total no. (%) | 155/276 (56.2) | 145/262 (55.3) | 10/14 (71.4) | 0.24 |
Smoking Index b — no./total no. (%) |  |  |  | 0.57 |
 0 | 192/220 (87.2) | 182/208 (87.5) | 10/12 (83.3) |  |
 1–199 | 7/220 (3.2) | 7/208 (3.4) | 0/12 (0) |  |
 200–399 | 6/220 (2.7) | 5/208 (2.4) | 1/12 (8.3) |  |
  ≥ 400 | 15/220 (6.8) | 14/208 (6.7) | 1/12 (8.3) |  |
 Median BMI (IQR) | 23.7 (22.0–25.4) | 23.7 (21.8–25.4) | 24.2 (22.5–25.5) | 0.55 |
Exposure to source of transmission within past 14 days — no./total no. c | ||||
 Recently visited Wuhan | 43/276 (15.6) | 42/262 (16.0) | 1/14 (7.1) | 0.37 |
 Had contact with people who visited Wuhan or were diagnosed with COVID-19 | 166/276 (60.1) | 157/262 (59.9) | 9/14 (64.3) | 0.75 |
 Contact with wildlife | 0 | 0 | 0 |  |
 Median incubation period (IQR) — days d | 6.0 (4.0–9.0) | 6.0 (4.0–9.0) | 6.0 (5.0–9.0) | 0.54 |
Fever on admission | ||||
 Patients — no./total no. (%) | 106/276 (38.4) | 99/262 (37.8) | 7/14 (50.0) | 0.36 |
 Median temperature (IQR)—°C | 37.2 (36.6–37.9) | 37.2 (36.6–37.9) | 37.6 (36.6–38.1) | 0.56 |
Distribution of temperature — no./total no. (%) | ||||
  < 37.5 °C | 170/276 (61.6) | 163/262 (62.2) | 7/14 (50.0) | 0.37 |
 37.5–38.0 °C | 54/276 (19.6) | 51/262 (19.5) | 3/14 (21.4) | 0.86 |
 38.1–39.0 °C | 41/276 (14.9) | 39/262 (14.9) | 2/14 (14.3) | 0.95 |
  > 39.0 °C | 11/276 (4.0) | 9/262 (3.4) | 2/14 (14.3) | 0.04 |
Fever during hospitalization | ||||
 Patients — no./total no. (%) | 207/276 (75.0) | 195 /262 (74.4) | 12/14 (85.7) | 0.34 |
 Median highest temperature (IQR)—°C | 38.2 (37.5–38.9) | 38.2 (37.4–38.9) | 38.9 (8.3–39.6) | 0.47 |
Distribution of temperature — no./total no. (%) | ||||
  < 37.5 °C | 69/276 (25.0) | 67/262 (25.6) | 2/14 (14.3) | 0.34 |
 37.5–38.0 °C | 57/276 (20.7) | 56/262 (21.4) | 1/14 (7.1) | 0.20 |
 38.1–39.0 °C | 107/276 (38.8) | 103/262 (39.3) | 4/14 (28.6) | 0.41 |
  > 39.0 °C | 43/276 (15.6) | 36/262 (13.7) | 7/14 (50.0) | < 0.01 |
Symptoms — no./total no. (%) | ||||
 Fever | 227/276 (82.2) | 219/262 (84.4) | 8/14 (57.1) | 0.01 |
 Conjunctival congestion | 2/276 (0.7) | 2/262 (0.8) | 0/14 (0) | 0.90 |
 Nasal congestion | 8/276 (2.9) | 8/262 (3.1) | 0/14 (0) | 0.66 |
 Headache | 24/276 (8.7) | 22/262 (8.4) | 2/14 (14.3) | 0.78 |
 Cough | 218/276 (78.0) | 204/262 (77.9) | 14/14 (100.0) | 0.02 |
 Sore throat | 26/276 (9.4) | 23/262 (8.8) | 3/14 (21.4) | 0.27 |
 Sputum production | 137/276 (49.6) | 127/262 (48.5) | 10/14 (71.4) | 0.16 |
 Fatigue | 141/276 (51.1) | 133/262 (50.8) | 8/14 (57.1) | 0.64 |
 Hemoptysis | 1/276 (0.4) | 0/262 (0) | 1/14 (7.1) | 0.06 |
 Shortness of breath | 42/276 (15.2) | 36/262 (13.7) | 6/14 (42.9) | < 0.01 |
 Nausea or vomiting | 23/276 (8.3) | 20/262 (7.6) | 3/14 (21.4) | 0.10 |
 Diarrhea | 6/276 (2.2) | 5/262 (1.9) | 1/14 (7.1) | 0.71 |
 Myalgia or arthralgia | 26/276 (9.4) | 24/262 (9.2) | 2/14 (14.3) | 0.84 |
Comorbidities — no./total no. (%) | ||||
 Any | 68/276 (24.6) | 56/262 (21.4) | 12/14 (85.7) | < 0.01 |
 Hypertension | 47/276 (17.0) | 39/262 (14.9) | 8/14 (57.1) | < 0.01 |
 Chronic obstructive pulmonary disease | 7/276 (2.5) | 5/262 (1.93) | 2/14 (14.3) | 0.04 |
 Diabetes | 14/276 (5.1) | 12/262 (4.6) | 2/14 (14.3) | 0.32 |
 Coronary heart disease | 12/276 (4.0) | 8/262 (5.2) | 4/14 (28.6) | < 0.01 |
 Cerebrovascular disease | 6/276 (2.2) | 5/262 (2.0) | 1/14 (7.1) | 0.71 |
 Cancer e | 3/276 (1.1) | 2/262 (0.8) | 1/14 (7.1) | 0.36 |