|
Age, years, median (quartile)
|
25 (24, 26)
|
29 (25, 33.25)
|
32 (28.75, 37)
|
31.5 (26, 38.25)
|
27 (25.5, 36)
|
< 0.001
|
|
Gender
| | | | | |
0.238
|
|
Male, n (%)
|
12 (70.6)
|
77 (64.2)
|
17 (85)
|
55 (76.4)
|
12 (70.6)
| |
|
Female, n (%)
|
5 (29.4)
|
43 (35.8)
|
3 (15)
|
17 (23.6)
|
5 (29.4)
| |
|
ALT, U/L, median (quartile)
|
20.6 (18.3, 22.4)
|
20.8 (19.1, 22.5)
|
22.3 (21.6, 23.8)
|
21.484 (19.8, 23.4)
|
16 (12.5, 22.0))
|
< 0.001
|
|
Fibroscan, Kpa median (quartile)
|
4.9 (4.2, 5.4)
|
5.3 (4.3, 6.5)
|
4.4 (4.0, 5.3)
|
4.8 (4.4, 5.4)
|
4.6 (4.0 ~ 5.1)
|
0.016
|
|
HBV DNA, Log IU/ml, median (quartile)
|
8.2 (8.2, 8.2)
|
7.7 (5.0, 8.2)
|
2.2 (1.6, 3.1)
|
3.3 (2.1, 4.3)
| |
< 0.001
|
|
HBeAg status
| | | | | |
< 0.001
|
|
Negative, n (%)
|
0 (0)
|
41 (34)
|
20 (100)
|
62 (86)
| | |
|
Positive, n (%)
|
17 (100)
|
78 (65)
|
0 (0)
|
10 (14)
| | |
|
Missing, n (%)
|
0 (0)
|
1 (1)
|
0 (0)
|
0 (0)
| | |
|
HBeAb status
| | | | | |
< 0.001
|
|
Negative, n (%)
|
17 (100)
|
70 (58.3)
|
1 (5)
|
13 (18.1)
| | |
|
Positive, n (%)
|
0 (0)
|
47 (39.2)
|
19 (95)
|
59 (81.9)
| | |
|
Missing, n (%)
|
0 (0)
|
3 (2.5)
|
0 (0)
|
0 (0)
| | |
|
qHBsAg, Log IU/ml, median (quartile)
|
4.6 (4.5, 4.7)
|
4.0 (3.3, 4.7)
|
2.9 (2.0, 3.2)
|
3.2 (2.3, 3.6)
| |
< 0.001
|
|
HBsAb status
| | | | | |
< 0.001
|
|
Negative, n (%)
|
15 (88)
|
106 (88)
|
20 (100)
|
67 (93)
| | |
|
Positive, n (%)
|
2 (12)
|
14 (12)
|
0 (0)
|
5 (7)
| | |
|
HBV genotype
| | | | | |
< 0.001
|
|
C, n(%)
|
2 (12)
|
30 (25)
|
3 (15)
|
15 (21)
| | |
|
B, n (%)
|
12 (71)
|
74 (62)
|
8 (40)
|
27 (38)
| | |
|
N, n (%)
|
0 (0)
|
2 (2)
|
9 (45)
|
23 (32)
| | |
|
O, n (%)
|
1 (6)
|
8 (1)
|
0 (0)
|
23 (32)
| | |
|
Missing, n(%)
|
2 (11)
|
6 (5)
|
0 (0)
|
1 (1)
| | |
