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Fig. 2 | BMC Infectious Diseases

Fig. 2

From: Combined therapy with ceftriaxone and doxycycline does not improve the outcome of meningococcal meningitis in mice compared to ceftriaxone monotherapy

Fig. 2

Effect of treatment with CRO + DOX on brain bleeding. Experimental design is as reported in Fig. 1. Brain hemispheres were collected 48 hpi, cut in 30 μm cryosections, and photographed with a digital camera to determine the number of bleedings. At least 5 slices/mouse were examined. a Macroscopical assessment of brain hemorrhages. Photos from a representative experiment out of the 3 performed is shown. b Enumeration of cerebral hemorrhages in animals treated with CRO (n = 17), CRO + DOX (n = 21), or saline (n = 10). Differences were analysed by the Dunn‘s multiple comparison test (*, p < 0.05)

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