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Table 4 Influence of haemoglobin genotype on P. falciparum infection in children under 3 years in Vihiga County, Kenya

From: Influence of blood group, Glucose-6-phosphate dehydrogenase and Haemoglobin genotype on Falciparum malaria in children in Vihiga highland of Western Kenya

Category Prevalence SMA
n = 137
n = 437
P- Valuea OR 95% CI P-Valueb
Haemoglobin Status SMA
 AA 477 (83.1) 123 (89.8) 354 (81.0) 0.001 Ref
 AS 93 (16.2) 11 (8.0) 82 (18.8) 0.116 0.012–1.124 0.063
 SS 4 (0.7) 3 (2.2) 1 (0.2) XX XX XX
  1. Prevalence in the haemoglobin genotypes in population studied are presented as n (percentage, %). Data shown are number (n) and proportions (%) of subjects. Odds ratios (OR) and 95% confidence intervals (95% CI) were determined using multivariate logistic regression controlling for age and sex. Non-severe malaria anaemia was used as reference category. SMA, severe malaria, non-severe malaria anaemia. AA, normal hemoglobin. AS, heterozygote sickle cell. SS, homozygote sickle cell. XX, multivariate logistic regression was not performed because the numbers were too few to run in the model