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Table 2 Median biomarker values at baseline and 6 months and mean change from baseline to 6 months among adults (≥ 18 years) starting ART in Kenya 2014 (N = 611)

From: Changes in D-dimer after initiation of antiretroviral therapy in adults living with HIV in Kenya

  Baseline 6 months Change baseline to 6 months
Median
(IQR)
Log median
(IQR)
Median
(IQR)
Log median
(IQR)
Mean log10 change
(95% CI)
p-value*
D-dimer (ng/mL) 516.4
(302.7–926.6)
2.7
(2.5–3.0)
390.0
(236.6–656.9)
2.6
(2.4–2.8)
−0.12
(−0.15, −0.09)
< 0.0001
Sex
 Male 448.0
(245.7–872.1)
2.7
(2.4–2.9)
290.1
(199.0–539.3)
2.5
(2.3–2.7)
− 0.15
(− 0.2, − 0.1)
0.14
 Female 566.1
(347.9–953.4)
2.8
(2.5–3.0)
430.2
(279.6–714.7)
2.6
(2.4–2.9)
− 0.10
(− 0.14, − 0.07)
 
Baseline log viral load cells/mL
 > 6.0 819.8
(466.8–1262.3)
2.9
(2.7–3.1)
397.8
(259.5–617.8)
2.6
(2.4–2.8)
− 0.28
(− 0.37, − 0.19)
< 0.01
 5.0–6.0 566.8
(320.2–970.4)
2.8
(2.5–3.0)
399.2
(246.1–723.3)
2.6
(2.4–2.9)
− 0.13
(− 0.17, − 0.09)
 4.0–4.9 461.8
(284.3–894.9)
2.7
(2.5–3.0)
410.3
(258.4–639.3)
2.6
(2.4–2.8)
− 0.08
(− 0.13, − 0.03)
 < 4.0 435.0
(258.7–683.1)
2.6
(2.4–2.8)
326.4
(199.0–590.6)
2.5
(2.3–2.8)
− 0.08
(− 0.14, 0.01)
Baseline TB
 No 495.9
(300.6–884.8)
2.7
(2.5–2.9)
390.2
(237.4–666.3)
2.6
(2.4–2.8)
−0.10
(− 0.13, − 0.07)
< 0.0001
 Yes 1230.3
(465.1–2586.3)
3.1
(2.7–3.4)
297.3
(199.0–572.8)
2.5
(2.3–2.8)
−0.43
(− 0.56, − 0.31)
  1. *p-values from Type 3 Tests of Fixed Effects