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Table 1 Characteristics at study enrollment of ART-naïve treatment eligible adults (≥ 18 years) living with HIV in Kenya and starting ART in 2014 according to enrollment D-dimer level, normal/low vs. high (N = 611)

From: Changes in D-dimer after initiation of antiretroviral therapy in adults living with HIV in Kenya

  Total Normal/low D-dimer
(< 500 ng/mL)
High D-dimer
(≥ 500 ng/mL)
 
N % N % N % p-value
611 100.0 300 49.1 311 50.9  
Enrollment D-dimer, median (IQR) 516.4 (302.7–926.6) 301.7 (199.0–397-6) 912.8 (690.2–1446.2) < 0.0001
Sex
 Male 211 34.5 117 39.0 94 30.2 0.02
 Female 400 65.5 183 61.0 217 69.8  
Age (years), median (IQR) 34 (29–43) 34 (29–43) 34 (29–43) 0.86
 < 25 52 8.5 29 9.7 23 7.4 0.60
 25–40 384 62.9 186 62.0 198 63.7  
 > 40 175 28.6 85 28.3 90 28.9  
CD4+ cells/mm3, median (IQR) 326 (194–442) 335 (221–451) 319 (177–435) 0.17
 > 500 78 12.8 39 13.0 39 12.5 0.42
 350–500 186 30.4 98 32.7 88 28.3  
 200–349 190 31.1 95 31.7 95 30.6  
 < 200 156 25.5 68 22.7 88 28.3  
 Missing 1 0.2 0 0.0 1 0.3  
Viral load copies/mL, median (IQR) 113,500 (23,600-399,000) 82,200 (15,800-294,000) 159,000 (33,400-501,000) 0.0001
 < 1000 (<log 3.0) 30 4.9 18 6.0 12 3.9 0.01
 1000–9999 (log 3.0–3.9) 57 9.3 34 11.3 23 7.4  
 10,000–99,999 (log 4.0- < 4.9) 201 32.9 107 35.7 94 30.2  
 100,000-1000,000 (log 5.0–5.9) 255 41.7 116 38.7 139 44.7  
 > 1000,000 (>log 6.0) 53 8.7 16 5.3 37 11.9  
 Missing 15 2.5 9 3.0 6 1.9  
BMI, median (IQR) 20.9 (18.9–22.9) 21.1 (19.1–22.9) 20.5 (18.6–23.0) 0.21
 Underweight (< 18.5) 114 18.7 48 16.0 66 21.2 0.17
 Normal (18.5–24.9) 425 69.6 219 73.0 206 66.2  
 Overweight & Obese (≥25) 72 11.8 33 11.0 39 12.5  
Current TB at study enrollment 31 5.1 9 3.0 22 7.1 0.02