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Table 1 Antimicrobial susceptibility profile of coagulase-negative Staphylococcus sp. (CoNS) isolates in asymptomatic and symptomatic central line-associated bloodstream infections

From: Asymptomatic central line-associated bloodstream infections in children implanted with long term indwelling central venous catheters in a teaching hospital, Sri Lanka

Antibiotic

CLABSI

P value

Symptomatic- CoNS

Asymptomatic- CoNS

S. epidermidis (n = 10)

S. hemolyticus (n = 6)

S. epidermidis (n = 54)

S. hemolyticus (n = 6)

S. schleiferi (n = 5)

S. lugdunensis (n = 5)

Ampicillin (30 μg)

2 (20%)

1 (17%)

47 (87.3%) *

6 (100%)

5 (100%)

5 (100%)

0.03*

Cefoxitin (30 μg)

2 (20%)

1 (17%)

45 (85.7%) **

6 (100%)

5 (100%)

5 (100%)

0.02**

Oxacillin

2 (20%)

1 (17%)

45 (85.7%) ***

6 (100%)

5 (100%)

5 (100%)

0.03***

Ciprofloxacin (5 μg)

1 (10%)

1 (17%)

45 (85.7%) α

4 (67%)

5 (100%)

5 (100%)

0.03α

Levofloxacin (5 μg)

2 (20%)

1 (17%)

45 (85.7%) μ

4 (67%)

4 (80%)

5 (100%)

0.03μ

Trimethoprim/ sulfamethoxazole (1.25/23.25 μg)

1 (10%)

1 (17%)

42 (79.3%)

4 (67%)

5 (100%)

5 (100%)

0.03

Amikacin (30 μg)

3 (30)

1 (17%)

42 (79.3%)

4 (67%)

5 (100%)

5 (100%)

0.03

Gentamicin (10 μg)

2 (20)

1 (17%)

42 (79.3%)

4 (67%)

5 (100%)

5 (100%)

0.03

Erythromycin (30 μg)

2 (20)

1 (17%)

42 (79.3%)

4 (67%)

5 (100%)

5 (100%)

0.03

Clindamycin (30 μg)

2 (20)

1 (17%)

42 (79.3%)

4 (67%)

5 (100%)

5 (100%)

0.03

vancomycin

0

0

0

0

0

0

–

Linezolid

0

0

0

0

0

0

–

Tigecycline

0

0

0

0

0

0

–

  1. P < 0.05 taken as significant
  2. * Ampicillin resistance is significantly low in S. epidermidis; ** Cefoxitin resistance is significantly low in S. epidermidis; *** Oxacillin resistance is significantly low in S. epidermidis; α Ciprofloxacin resistance is significantly low in S. epidermidis; μ Levofloxacin resistance is significantly low in S. epidermidis