Mycobacterial antigens in pleural fluid mononuclear cells to diagnose pleural tuberculosis in HIV co-infected patients

Table 6 Diagnostic validity of different tests performed on pleural fluid samples by using three reference standards

	CRS		Culture		Culture & N-PCR
	SN	SP	SN	SP	SN	SP
Culture	41	100
Nested-PCR	53	89	77	71
Real-time PCR	6	100	15	100	12	100
AFB Microscopy	12	100	23	96	23	100
Mycobacterial antigens
Cell wall antigen	38	78	31	64	41	71
LAM	47	100	54	71	53	75
Heterogeneous antigens	41	56	54	64	47	62
Secreted antigen	38	78	39	68	35	67
Secreted antigen or LAM	56	78	54	54	59	58
Any 4 antigens	72	44	69	32	76	37
Culture, nested-PCR or any antigen	88	33
Culture, nested-PCR or LAM	78	89

ISSN: 1471-2334