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Table 6 Drug-resistant profiles of 684 drug-resistant tuberculosis cases stratified by resistance to isoniazid and rifampicin

From: Age-stratified anti-tuberculosis drug resistance profiles in South Korea: a multicenter retrospective study

 Other resistant TB
(n = 136)
Hr-TB
(n = 316)
RR-TB
(n = 53)
MDR-TB
(n = 179)
Total
(n = 684)
Resistant to
 INH0 (0.0%)316 (100.0%)0 (0.0%)179 (100.0%)495 (72.4%)
 RIF0 (0.0%)0 (0.0%)53 (100.0%)179 (100.0%)232 (33.9%)
 Rfb0 (0.0%)0 (0.0%)36 (67.9%)110 (61.5%)146 (21.3%)
 EMB9 (6.6%)27 (8.5%)1 (1.9%)94 (52.5%)131 (19.2%)
 PZA16 (11.8%)6 (1.9%)1 (1.9%)66 (36.9%)89 (13.0%)
 Km4 (2.9%)2 (0.6%)1 (1.9%)24 (13.4%)31 (4.5%)
 Am3 (2.2%)2 (0.6%)1 (1.9%)21 (11.7%)27 (3.9%)
 Cm11 (8.1%)2 (0.6%)1 (1.9%)20 (11.2%)34 (5.0%)
 Sm64 (47.1%)43 (13.6%)2 (3.8%)59 (33.0%)168 (24.6%)
 Lfx34 (25.0%)4 (1.3%)1 (1.9%)34 (19.0%)73 (10.7%)
 Mfx29 (21.3%)3 (0.9%)1 (1.9%)31 (17.3%)64 (9.4%)
 Ofx32 (23.5%)4 (1.3%)1 (1.9%)34 (19.0%)71 (10.4%)
 Pto0 (0.0%)25 (7.9%)0 (0.0%)20 (11.2%)45 (6.6%)
 Cs0 (0.0%)1 (0.3%)0 (0.0%)5 (2.8%)6 (0.9%)
 PAS2 (1.5%)29 (9.2%)0 (0.0%)27 (15.1%)58 (8.5%)
Resistance to any FQsa34 (25.0%)4 (1.3%)1 (1.9%)36 (20.1%)75 (11.0%)
Resistance to any SLIDsb12 (8.8%)3 (0.9%)1 (1.9%)26 (14.5%)42 (6.1%)
  1. Abbreviations: INH isoniazid, RIF rifampicin, Rfb rifabutin, EMB ethambutol, PZA pyrazinamide, Km kanamycin, Am amikacin, Cm capreomycin, Sm streptomycin, Lfx levofloxacin, Mfx moxifloxacin, Ofx ofloxacin, Pto prothionamide, Cs cycloserine, PAS para-aminosalicylic acid, FQs fluoroquinolones, SLIDs second-line injectable drugs
  2. aAny fluoroquinolones refer to levofloxacin, moxifloxacin, or ofloxacin
  3. bAny second-line injectable drugs refer to kanamycin, amikacin, or capreomycin