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Table 3 Reported factors associated with cryptococcal antigenemia among HIV infected patients in resource limited settings, 2007–2018

From: Cryptococcal antigenemia and its predictors among HIV infected patients in resource limited settings: a systematic review

Author (s) Reported predictors for positive CrAg test
Vidal et al. [28] No data
Ganiem et al. [29] No data
Cheryl et al. [30] No data
Beyene et al. [31] Being ART naive and ART-defaulter
Meya et al. [32] A cryptococcal diagnosis during follow-up
Rugemalila et al. [33] No data
Longley et al. [34] No data
Hailu et al. [35] Being male, living in rural areas, being hospitalized
Letang et al. [36] No data
Christopher et al. [37] Female gender, CD4 count of < 200 cell/μL
Williams et al. [38] No data
Alemu et al. [39] An increasing age, self-reported fever, CD4 count < 100 cells and site of screening.
Derbie et al. [40] Gender
Mamuye et al. [41] Lower median CD4, history of cryptococcal disease, having symptoms of headache, head stiffness
Oyella et al. [42] Low body mass index, CD4+ count of less than 50 cells/mm3, recent diagnosis of HIV infection and meningeal signs
Ogouyemi et al. [18] Body mass index< 18.5 kg/m2, an alteration of the general condition with a CD4 lymphocyte counts< 50cells/μL
Drain et al. [43] CD4 counts < 50 cells/μL
Mdodo et al. [44] male sex, headache, blurred vision and previous antifungal drug use
Micol et al. [45] Countryside residence, headache, body mass index < 15.4 kg/m2, CD4+ count < 50 cells/mm3, male gender
Jarvis et al. [46] Baseline CD4 cell count, incident cryptococcal meningitis, history of cryptococcal disease
Wajanga et al. [47] CD4 counts of < 100 cells, altered mental status, neck stiffness, fever
Magambo et al. [48] Age, body mass index, CD4 count and WHO stage