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Table 3 Laboratory features of COVID-19 patients in Shiraz, South of Iran; presented as either mean ± SD, or frequency

From: Epidemiological and clinical features of 2019 novel coronavirus diseases (COVID-19) in the South of Iran

Laboratory FindingsNormal ValueAll patients
n = 113
Sever
n = 11
Not Sever
n = 102
P.valueDead
n = 9
Live
n = 104
P.value
White blood cell count3.5–9.56.06 (±2.50)6.62 (±2.68)6.00 (±2.49)0.4386.83 (±2.94)6.00 (±2.47)0.341
 Leukopenia10 (9)0 (0)10 (100)0.4241 (10)9 (90)0.484
 Normal89 (80.2)9 (10.1)80 (89.9)6 (6.7)83 (93.3)
 Leukocytosis12 (10.8)2 (16.7)10 (83.3)2 (16.7)10 (83.3)
Neutrophil count (a109/L)1.8–6.34.60 (±2.2)10.33 (±0)4.37 (± 1.93)0.0066.49 (± 3.47)4.26 (± 1.83)0.064
 1.8–6.320 (76.9)0 (0)20 (100)0.2312 (10)18 (90)0.218
  > 6.36 (23.1)1 (16.7)5 (83.3)2 (33.3)4 (66.7)
Lymphocyte count (a109/L)1.1–3.21.16 (±0.66)1.37 (± 0.62)1.14 (± 0.66)0.3861.09 (±0.64)1.16 (±0.66)0.791
  < 150014 (12.6)4 (28.6)10 (71.4)0.030a3 (21.4)11 (78.6)0.141
 1.5–3.271 (64)4 (5.6)53 (94.4)4 (5.6)67 (94.4)
  > 3.226 (23.4)3 (11.5)23 (88.5)2 (7.7)24 (92.3)
Monocyte count (a109/L)0.1–0.60.49 (±0.34)0.46 (± 0)0.50 (±0.38)0.9390.46 (± 0)0.50 (± 0.38)0.939
 Normal5 (83.3)1 (20)4 (80)1.0001 (20)4 (80)1.000
 Increase Monocyte count1 (16.6)0 (0)1 (100)0 (0)1 (100)
Hemoglobin (g/L)12–17.513.54 (±2.39)13.28 (±1.53)13.57 (±2.47)0.70613.02 (±2.26)13.58 (±2.41)0.500
Hematocrit (%)36–5440.42 (±4.69)37.05 (±10.81)40.66 (±4.29)0.30140.02 (±6.6)40.50 (± 4.3)0.838
Platelet count150–450220.92 (±105.66)220 (±108.82)220.98 (±105.87)0.985199.55 (±104.24)222.85 (±106.09)0.791
 Thrombocytopenia17 (15.6)2 (11.8)15 (88.2)0.6761 (5.9)16 (94.1)0.927
 Normal80 (73.4)7 (8.8)73 (91.3)7 (8.8)73 (91.3)
 Thrombocytosis12 (11.0)2 (16.7)10 (83.3)1 (8.3)11 (91.7)
Prothrombin Time (S)9.4–13.515.35 (±2.38)16.30 (±2.39)15.25 (±2.37)0.16716.70 (± 1.54)15.23 (± 2.41)0.077
 Normal25 (22.1)2 (8)23 (92)0.7960 (0)25 (100)0.249
 Prolonged88 (77.9)9 (10.2)79 (89.8)9 (10.2)79 (89.8)
Partial Thromboplastin Time (S)25–36.537.61 (±8.49)37.81 (±12.36)37.59 (±8.02)0.93435.11 (± 10.48)37.84 (± 8.31)0.357
 Decreased1 (0.9)2 (100)0 (0)0.000a1 (50)1 (50)0.100
 Normal57 (53.3)2 (3.6)54 (96.4)4 (7.1)52 (92.9)
 Prolonged49 (45.8)7 (14.3)42 (85.7)4 (8.2)45 (91.8)
International Normalized Ratio0–1.11.32 (±0.23)1.85 (±0.49)1.28 (±0.15)0.000a1.64 (± 0.32)1.25 (± 0.13)0.000a
Blood urea nitrogen (mg/dL)7–2016.80 (±5.81)17.34 (±6.57)16.75 (±5.76)0.76217.67 (± 16.73)16.73 (± 5.68)0.663
  ≤ 2082 (76.6)8 (9.8)74 (90.2)1.0006 (7.3)76 (92.7)1.000
  > 2025 (23.4)2 (8)23 (92)2 (8)23 (92)
Creatinine (mg/dL)0.6–1.21.13 (±0.35)1.22 (±0.38)1.12 (±0.35)0.4181.02 (±0.29)1.14 (±0.36)0.386
  ≤ 1.269 (64.5)6 (8.7)63 (91.3)0.7416 (8.7)63 (91.3)0.709
  > 1.238 (35.5)4 (10.5)34 (89.5)2 (5.3)36 (94.7)
Sodium (mmol/L)135–145137.7(±5.12)137.13 (±4.53)137.73 (±5.21)0.717138.91 (±5.74)137.56 (±5.09)0.478
Potassium (mmol/L)3.5–54.1(±0.6)3.84 (±0.46)4.08 (±0.57)0.1954.34 (± 0.68)4.04 (0.56)0.478
Lactate dehydrogenase (U/L)0–250686.23 (±509.39)686.23 (± 509.39)NA1116.5 (± 1059.95)628.86 (± 431.66)0.214
Aspartate aminotransferase (U/L)15–4047.00 (±30.86)49.00 (± 0)47.00 (± 33.33)1.00047 (± 0)47 (± 33.33)1.000
Alanine aminotransferase (U/L)9–5035.87 (±36.48)32.00 (± 0)36.42 (± 39.36)0.92032.00 (± 0)36.42 (±39.36)0.920
Albumin (g/L)3.4–5.43.90 (±0.46)3.90 (±0)3.90 (±0.47)0.9863.90 (±0.20)3.90 (± 0.49)0.974
Total bilirubin (mmol/L)0–1.40.69 (±0.30)0.64 (±0)0.69 (±0.31)0.8660.38 (±0.21)0.73 (± 0.29)0.063
Direct Bilirubin (mmol/L)0–0.30.34 (±0.16)0.31(± 0)0.34 (±0.16)0.8460.23 (± 0.10)0.35 (±0.16)0.333
C reactive Protein (mg/L)0–834.32 (±20.40)44.00 (±24.74)33.33 (±19.79)0.11635.00 (± 25.27)34.28 (±20.23)0.934
  < 89 (8.3)0 (0)9 (100)0.1270 (0)9 (100)0.616
 8–5072 (66.7)5 (6.9)67 (93.1)5 (6.9)67 (93.1)
  ≥ 5027 (25)5 (18.5)22 (81.5)1 (3.7)26 (96.3)
Erythrocyte sedimentation rate (mm/h)0–2045.05 (±21.93)45.66 (±22.39)34 (±0)0.61941.50 (± 24.89)46.00 (± 21.93)0.726
  < 201 (0.9)0 (0)1 (100)1.0000 (0)1 (100)1.000
  ≥ 2018 (15.9)1 (5.6)17 (94.4)4 (22.2)14 (77.8)
PH7.35–7.457.35 (0.29)7.41 (±0.05)7.33 (±0.32)0.567   
 Acidosis8 (7.1)1 (16.7)5 (83.3)0.7270 (0)6 (100)0.394
 Normal28 (24.8)5 (17.9)23 (82.1)5 (17.9)23 (82.1)
 Alkaline3 (2.7)0 (0)3 (100)1 (33.3)2 (66.7)
Arterial Blood Gas
 PCO235–4844.08 (±10.73)42.45 (± 6.61)44.26 (± 11.11)0.61546.20 (± 15.27)43.89 (± 10.33)0.563
 PO24031.24(±13.74)38.88 (±17.50)30.35 (±13.06)0.05147.40 (± 27.23)29.73 (10.83)0.000a
 HCO335–4825.62 (±3.58)25.91 (±3.25)25.58 (±3.63)0.78925.82 (± 4.35)25.60 (± 3.53)0.868
  1. NA: Not applicable; a indicator of significant correlation