Objective cognitive performance and subjective complaints in patients with chronic Q fever or Q fever fatigue syndrome

Table 2 Comparison of cognitive domains with MANCOVA, unadjusted and adjusted for age and premorbid IQ, for all study participants and separately for participants without poor performance validity

	Chronic Q fever		Control group			QFS		Control group
	Mean	(SE)	Mean	(SE)	p-value	Mean	(SE)	Mean	(SE)	p-value
All participants (unadjusted)	n = 30		n = 23			n = 32		n = 21
Episodic Memory	−0.752	(0.160)	0.162	(0.183)	< 0.001	0.397	(0.155)	0.112	(0.192)	0.255
Working Memory	−0.330	(0.142)	0.195	(0.162)	0.018	− 0.006	(0.152)	0.337	(0.187)	0.160
Processing Speed	−0.163	(0.089)	−0.070	(0.101)	0.493	0.135	(0.065)	0.108	(0.081)	0.798
Executive Functions	−0.316	(0.116)	0.188	(0.132)	0.006	0.027	(0.110)	0.195	(0.136)	0.342
All participants (adjusted¹)	n = 30		n = 23			n = 32		n = 21
Episodic Memory	−0.595	(0.158)	−0.043	(0.183)	0.035	0.373	(0.147)	0.192	(0.181)	0.243
Working Memory	−0.232	(0.134)	0.067	(0.156)	0.175	0.056	(0.132)	0.304	(0.163)	0.218
Processing Speed	−0.080	(0.086)	−0.177	(0.099)	0.488	0.096	(0.068)	0.160	(0.084)	0.113
Executive Functions	−0.211	(0.115)	0.052	(0.134)	0.165	0.048	(0.111)	0.157	(0.137)	0.184
Excluding participants with poor performance validity	n = 18^a		n = 18^b			n = 25^a,c		n = 15^b
Episodic Memory	−0.117	(0.184)	0.193	(0.184)	0.283	0.589	(0.151)	0.319	(0.199)	0.305
Working Memory	−0.134	(0.214)	0.260	(0.214)	0.241	0.188	(0.148)	0.496	(0.195)	0.234
Processing Speed	0.111	(0.093)	−0.139	(0.093)	0.091	0.080	(0.084)	0.186	(0.111)	0.467
Executive Functions	−0.016	(0.133)	0.222	(0.133)	0.253	0.192	(0.095)	0.319	(0.125)	0.440

ISSN: 1471-2334