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Table 2 Comparison of cognitive domains with MANCOVA, unadjusted and adjusted for age and premorbid IQ, for all study participants and separately for participants without poor performance validity

From: Objective cognitive performance and subjective complaints in patients with chronic Q fever or Q fever fatigue syndrome

  Chronic Q fever Control group   QFS Control group  
Mean (SE) Mean (SE) p-value Mean (SE) Mean (SE) p-value
All participants (unadjusted) n = 30   n = 23    n = 32   n = 21   
 Episodic Memory −0.752 (0.160) 0.162 (0.183) < 0.001 0.397 (0.155) 0.112 (0.192) 0.255
 Working Memory −0.330 (0.142) 0.195 (0.162) 0.018 − 0.006 (0.152) 0.337 (0.187) 0.160
 Processing Speed −0.163 (0.089) −0.070 (0.101) 0.493 0.135 (0.065) 0.108 (0.081) 0.798
 Executive Functions −0.316 (0.116) 0.188 (0.132) 0.006 0.027 (0.110) 0.195 (0.136) 0.342
All participants (adjusted1) n = 30   n = 23    n = 32   n = 21   
 Episodic Memory −0.595 (0.158) −0.043 (0.183) 0.035 0.373 (0.147) 0.192 (0.181) 0.243
 Working Memory −0.232 (0.134) 0.067 (0.156) 0.175 0.056 (0.132) 0.304 (0.163) 0.218
 Processing Speed −0.080 (0.086) −0.177 (0.099) 0.488 0.096 (0.068) 0.160 (0.084) 0.113
 Executive Functions −0.211 (0.115) 0.052 (0.134) 0.165 0.048 (0.111) 0.157 (0.137) 0.184
Excluding participants with poor performance validity n = 18a   n = 18b    n = 25a,c   n = 15b   
 Episodic Memory −0.117 (0.184) 0.193 (0.184) 0.283 0.589 (0.151) 0.319 (0.199) 0.305
 Working Memory −0.134 (0.214) 0.260 (0.214) 0.241 0.188 (0.148) 0.496 (0.195) 0.234
 Processing Speed 0.111 (0.093) −0.139 (0.093) 0.091 0.080 (0.084) 0.186 (0.111) 0.467
 Executive Functions −0.016 (0.133) 0.222 (0.133) 0.253 0.192 (0.095) 0.319 (0.125) 0.440
  1. 1Adjusted for age and premorbid IQ
  2. a1 missing value of performance validity
  3. b2 missing values of performance validity
  4. c1 missing value of premorbid IQ
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