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Table 4 Comparisons of prognostic factors of 14-day mortality between surviving and non-surviving patients with candidemia

From: Delta neutrophil index as a predictive and prognostic factor for Candidemia patients: a matched case-control study

 Survivor
N = 57 (%)
Non-survivor
N = 13 (%)
pAdjusted ORs (95% CI)p
Age (mean ± SD)65.81 ± 13.36172.46 ± 18.7150.959  
Sex
 Female27 (47.4)3 (23.1)0.110  
 Male30 (57.1)10 (76.9)   
Co-morbidities
 MaCabe classification  0.163  
  Non-fatal12 (21.2)1 (7.7)   
  Ultimately fatal43 (75.4)10 (76.9)   
  Rapidly fatal2 (3.5)2 (15.4)   
Severity of infection
 Pitt bacteremia score (median, IQR)0 (0.0–2.0)4.0 (1.0–5.0)< 0.0011.187 (0.890–1.584)0.244
 Septic shock10 (17.5)8 (61.5)0.0037.635 (1.159–50.290)0.035
 Candia colonization15 (26.3)4 (30.8)0.739  
 Candida score ≥ 311 (19.3)6 (46.2)0.0420.900 (0.225–3.609)0.882
 DNI_D1, %3.4 (2.2–5.3)7.4 (4.0–22.0)0.0021.156 (1.039–1.287)0.008
 DNI_48, %2.0 (0.5–2.9)6.1 (2.1–14.4)0.0151.226 (1.007–1.494)0.043
 Leukocytes, 103/uL (mean ± SD)10,831.58 ± 6010.19010,931 ± 7311.8710.139  
 CRP (median, IQR)66.0 (39.0–145.0)115.5 (84.2–136.0)0.0361.003 (0.996–1.009)0.412
 Procalcitonin (median, IQR)0.47 (0.2–1.9)1.0 (0.38–2.09)0.303  
 Time to positive, hours, (median, IQR)48.0 (34.0–72.0)31.0 (26.5–53.0)0.066  
 Time to antifungal therapy, hours (median, IQR)60 (42.0–96.0)36 (12.5–42.0)0.0130.968 (0.933–1.004)0.079
 Duration of Clear- up, days, (median, IQR)5 (3.0–9.5)4.5 (4.0–5.0)0.638  
  1. DNI Delta neutrophil index, IQR Interquartile ranges, SD Standard deviation, CRP C-reactive protein