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Fig. 1 | BMC Infectious Diseases

Fig. 1

From: A blood RNA transcript signature for TB exposure in household contacts

Fig. 1

Protein-protein network of the 186 exposure genes. Each circle represents a protein encoded by a gene. Colors were assigned proteins that belong to three overrepresented pathways relevant to TB infection. Type 1 interferon signaling pathway (red circles: IFI6, IFITM2, IRF7, ISG15, OASL, RSAD2, XAF1); Inflammatory response (blue circles: CLEC7A, CLU, CXCL1, CXCL5, FFAR2, FPR1, IL1R1, IL1RN, PF4, PF4V1, PLSCR1, PPBP, TNFAIP6, TPST10); Neutrophil mediated immunity (green circles: ANXA3, CEACAM3, CXCL1, CXCL5, CXCR1, FCGR2A, FCGR3B, FOLR3, FPR1, GPR97, PGLYRP1, PPBP, RAP1A, SLPI, TNFAIP6)

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