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Table 2 Findings of three types of genetic test assays of nasopharyngeal specimen upon admission

From: Neurogenic pulmonary edema following febrile status epilepticus in a 22-month-old infant with multiple respiratory virus co-detection: a case report

  Real-time RT-PCRa (Cq value) BIOFIRE FILMARRAY
Respiratory Panelb
Metagenomic analysis using NGS; number of reads
(Total, 17,937,281 reads obtained as RNA-Seq metagenomics)
Nasopharyngeal specimen
Upon admission
Human coronavirus HKU1 (21.5)
Influenza C virus (19.7)
Human parainfluenza virus 2 (36.4)
(16 viruses undetectable)
Human coronavirus HKU1 +
Human parainfluenza virus 2 +
(12 viruses and 3 bacteria undetectable)
Human coronavirus HKU1 714 reads (0.004%)
Influenza C virus 4698 reads (0.026%)
Human 16,716,897 reads (93.1%)
(No other viruses read)
Nasopharyngeal specimen
Hospital day 2
Human coronavirus HKU1 (30.0)
Influenza C virus (25.9)
(17 viruses undetectable)
NE NE
Serum on admission NE NE No viruses read
Cerebrospinal fluid upon admission NE NE No viruses read
  1. a Targeting nineteen respiratory viruses: influenza A (subtype H1pdm and H3), influenza B and C, human metapneumovirus, human respiratory syncytial viruses A and B, human bocavirus, rhinovirus, human respirovirus 1 and 3, human parainfluenza viruses 2 and 4, human adenoviruses 2 and 4, human coronaviruses NL63, OC43, HKU1 and 229E
  2. b Targeting fourteen respiratory viruses: influenza A and B, human metapneumovirus, human respiratory syncytial virus, rhinovirus/enterovirus, human parainfluenza viruses 2 and 4, human adenoviruses 2 and 4, human adenovirus, human coronaviruses NL63, OC43, HKU1 and 229E. Targeted bacteria: Bordetella pertussis, Chlamydophila pneumoniae, Mycoplasma pneumoniae. Influenza C virus was not included in the targeted panel and was thus undetectable
  3. NE not examined. +, positive