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Table 2 Characteristics of patients with CC398 PJI

From: Epidemiology and risk factors of Staphylococcus aureus CC398 bone and joint infections

 CC 398 PJI (n = 23)Non CC 398 PJI (n = 121)UnivariateMultivariate
P valueP valueOR (IC 95%)
Age (years), mean ± SD67.7 (±12.3)73.6 (±12.3)0.0410.0340.9 (0.9–0.99)
Male sex, n (%)11 (48)65 (54)0.77  
Mc Cabe Score
 Non fatal, n (%)18 (78)114 (94.2)0.0160.0055.1 (1.6–15.3)
 Ultimately fatal, n (%)5 (22)6 (5)   
 Rapidly fatal, n (%)0 (0)1 (0.8)   
MSSA, n (%)23 (100)108 (89)0.13  
Charlson’s comorbidity score, mean ± SD2.04 (±1.89)1.56 (±1.61)0.27  
Year of infection
 20102 (8.7)14 (11)0.1NT 
 20112 (8.7)9 (7.3)   
 20122 (8.7)18 (15)   
 20134 (17)13 (11)   
 20141 (4.3)17 (14)   
 20152 (8.7)16 (13)   
 20162 (8.7)24 (20)   
 20178 (35)12 (9.8)   
Recent hospitalisation (< 1 yr), n (%)13 (57)74 (60)0.92  
BJI Type
 Shoulder, n (%)1 (4.3)5 (4.1)1  
 Hip, n (%)16 (70)75 (62)0.65  
 Knee, n (%)6 (26)40 (33)0.68  
 Ankle, n (%)01 (0.8)1  
Chronic BJI (i.e. evolution delay > 4 weeks)5 (28)51 (42)0.37  
Occurrence of infection after primary arthroplasty
Delay (months)23 (±49.3)44.4 (±59.2)0.023NT 
 < 3 months, n (%)14 (61)44 (36)0.049NT 
 3–12 months, n (%)3 (13)17 (14)1  
 12 months, n (%)7 (30)60 (50)0.14  
Bacteremia, n (%)8 (35)32 (26)0.57  
BJI mechanisms
 haematogenous, n (%)3 (13)37 (31)0.14  
 inoculation, n (%)20 (87)74 (61)0.0320.0203.7 (1.2–11.3)
 Contiguity, n (%)010 (8.3)0.36  
Clinical features
 Fever, n (%)10 (43)48 (40)0.66  
 Sinus tract, n (%)7 (30)48 (40)1  
 Abscess, n (%)3 (13)12 (9.9)0.4  
Biological features
 Maximum CRP value (mg/L)163 (±69.1)171 (±120)0.9  
  1. MSSA Methicillin susceptible Staphylococcus aureus, BJI Bone and joint infection, NT Not included in the final model
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