Table 1 Characteristics of patients with CC398 Bone and joint infections
From: Epidemiology and risk factors of Staphylococcus aureus CC398 bone and joint infections
CC 398 (n = 124) | Non CC 398 (n = 834) | Univariate P value | |
|---|---|---|---|
Age (years), mean ± SD | 62.2 (±18.6) | 64.3 (±18.7) | 0.24 |
Male sex, n (%) | 91 (73) | 573 (69) | 0.34 |
Mc Cabe Score | |||
Non fatal, n (%) | 110 (88.7) | 761 (91.2) | 0.19 |
Ultimately fatal, n (%) | 13 (10.5) | 63 (7.6) | |
Rapidly fatal, n (%) | 1 (0.8) | 10 (1.2) | |
MSSA, n (%) | 120 (97) | 701 (84) | < 0.001 |
Charlson’s comorbidity score, mean ± SD | 2.46 (±2.22) | 2.08 (±1.94) | 0.073 |
Year of infection | |||
2010 | 4 (3.2) | 89 (11) | < 0.001 |
2011 | 2 (1.6) | 100 (12) | |
2012 | 4 (3.2) | 92 (11) | |
2013 | 15 (12) | 88 (11) | |
2014 | 20 (16) | 118 (14) | |
2015 | 18 (15) | 120 (14) | |
2016 | 26 (21) | 126 (15) | |
2017 | 35 (28) | 101 (12) | |
Recent hospitalisation (< 1 yr), n (%) | 62 (50) | 474 (57) | 0.18 |
Surgery (< 1 yr), n (%) | 68 (55) | 428 (51) | 0.53 |
BJI Type | |||
Arthritis, n (%) | 8 (6.5) | 47 (5.6) | 0.87 |
Osteomyelitis, n (%) | 15 (12,1) | 119 (14.3) | 0.52 |
Vertebral osteomyelitis, n (%) | 0 | 6 (0.7) | 1 |
Diabetic foot osteomyelitis, n (%) | 37 (29.8) | 207 (24.8) | 0.28 |
BJI related to decubitus ulcer, n (%) | 4 (3.2) | 40 (4.8) | 0.58 |
BJI related to peripheral vascular disease | 7 (5.7) | 101 (12.1) | 0.05 |
Orthopaedic device infection, n (%) | 53 (42.7) | 314 (37.7) | 0.31 |
including PJI, n (%) | 23 (18.6) | 121 (14.5) | 0.3 |
including osteosynthesis infection, n (%) | 29 (23.4) | 184 (22.1) | 0.83 |
including vertebral ODI, n (%) | 1 (0.8) | 9 (1.1) | 1 |
BJI characteristics | |||
Evolution delay (months) | 28 (±62.9) | 37.6 (±101.7) | 0.32 |
Chronic BJI (i.e. evolution delay > 4 weeks), n (%) | 49 (75) | 270 (68) | 0.29 |
Bacteremiae, n (%) | 20 (16) | 87 (10) | 0.084 |
BJI mechanisms | |||
Haematogenous, n (%) | 4 (3.2) | 49 (5.9) | 0.32 |
Inoculation, n (%) | 62 (50) | 369 (44) | 0.27 |
Contiguity, n (%) | 58 (47) | 416 (50) | 0.58 |