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Table 2 Cure and egg reduction rates of single and multiple dose mebendazole against hookworm infections among school-aged children from Burie and Debre Elias towns, January – June 2019

From: Efficacy of a single dose versus a multiple dose regimen of Mebendazole against hookworm infections among school children: a randomized open-label trial

 Single doseMultiple dose
No. of Infections before treatment (%)52 (100%)51
No. of cured after treatment1649
CR (95% CI)30.8 (19.2–44.2)96.1 (90.2–100)
EPG arithmetic mean
 Before treatment (95% CI)1216 (845.8–1586.86)1134.3 (864.4–1404.2)
 After treatment (95% CI)378.04 (237.1–510.99)5.88 (− 2.85–14.6
 ERR(95% CI)68.9% (48.07–73.14)99.5% (98.97–100)
EPG geometric mean
 Before treatment (95% CI)826.1 (651.1–1039.7)821.3 (656.3–1024.8)
 After treatment (95% CI)61.3 (27.8–133.0)0.4 (0.0–1.0)
 ERR (95% CI)92.6% (87.5–96.4)99.9% (99.8–100)
 Infection intensity after treatmentN (%)N (%)
  Light (1–1999 EPG)35 (67.1%)3 (5.9%)
  Moderate (2000–3999)1 (1.9%)
  Heavy (> = 4000)