Skip to main content

Table 2 Cure and egg reduction rates of single and multiple dose mebendazole against hookworm infections among school-aged children from Burie and Debre Elias towns, January – June 2019

From: Efficacy of a single dose versus a multiple dose regimen of Mebendazole against hookworm infections among school children: a randomized open-label trial

 

Single dose

Multiple dose

No. of Infections before treatment (%)

52 (100%)

51

No. of cured after treatment

16

49

CR (95% CI)

30.8 (19.2–44.2)

96.1 (90.2–100)

EPG arithmetic mean

 Before treatment (95% CI)

1216 (845.8–1586.86)

1134.3 (864.4–1404.2)

 After treatment (95% CI)

378.04 (237.1–510.99)

5.88 (− 2.85–14.6

 ERR(95% CI)

68.9% (48.07–73.14)

99.5% (98.97–100)

EPG geometric mean

 Before treatment (95% CI)

826.1 (651.1–1039.7)

821.3 (656.3–1024.8)

 After treatment (95% CI)

61.3 (27.8–133.0)

0.4 (0.0–1.0)

 ERR (95% CI)

92.6% (87.5–96.4)

99.9% (99.8–100)

 Infection intensity after treatment

N (%)

N (%)

  Light (1–1999 EPG)

35 (67.1%)

3 (5.9%)

  Moderate (2000–3999)

1 (1.9%)

–

  Heavy (> = 4000)

–

–