Conditional exact method for comparing two independent Poisson rates using a binomial distribution | Cox proportional hazard | GEE Poisson | Prentice Williams Peterson-Total time | |
---|---|---|---|---|
Outcome | Rate ratio | Hazard ratio | Rate ratio | Hazard ratio |
Assumption(s) |
* Rate of events constant over time * Groups are considered to be equally exposed [52] |
* Proportional hazard assumption (hazard ratio over time should be constant) * Independence assumption (estimate only for 1st event) [52] |
* Rate of events constant over time [52] * Measurements are independent across subjects * Measurements may be correlated within subjects | * Event specific baseline hazard (baseline hazard for k^{th} event allowed to be different) [51] |
Check assumptions in HAVANA | Assumption for constant rate over time violated among unvaccinated | Proportional hazard assumption not violated | Assumption for constant rate over time violated among unvaccinated | Assumption for event-specific hazard not violated |