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Table 2 Performances of APRI and FIB-4 in predicting cirrhosis using transient elastography as a gold standard

From: Diagnostic performance of APRI and FIB-4 for confirming cirrhosis in Indonesian HIV/HCV co-infected patients

 APRI 1FIB-4 1.66
Se (95% CI)48.4% (35.7–61.2)53.1% (40.2–65.7)
Sp (95% CI)95.0% (90.3–97.8)92.5% (87.1–96.0)
PPV (95% CI)79.5% (65.3–88.8)73.9% (61.0–83.6)
NPV (95% CI)82.1% (78.3–85.3)83.1% (79.0–86.4)
LR+ (95% CI)9.6 (4.7–19.8)7.0 (3.9–12.7)
LR- (95% CI)0.5 (0.4–0.7)0.5 (0.3–0.6)
Ac (95% CI)81.6% (75.9–86.5)81.1% (75.4–86.0)
AUC (95% CI)0.72 (0.63–0.80)0.73 (0.65–0.81)
  1. Se: sensitivity; Sp: specificity; PPV: positive predictive value; NPV: negative predictive value; LR-: negative likelihood ratio; LR+: positive likelihood ratio; Ac: accuracy; K: kappa; AUROC: area under the receiving operator curve
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