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Table 1 The demographic data of patients of acute Q fever, scrub typhus and, murine typhus

From: Serum C-reactive protein and procalcitonin values in acute Q fever, scrub typhus, and murine typhus

 

Acute Q fever (n = 115)

Scrub typhus (n = 55)

Murine typhus (n = 19)

Total (n = 189)

Demographics

 Male

108 (93.9%)

33 (60.0%)

15 (78.9%)

156 (82.5%)

 Age (years) (mean ± SD)

44.8 ± 12.1

44.3 ± 16.9

49.8 ± 14.6

45.1 ± 13.9

 Admission

93 (80.9%)

52 (94.5%)

18 (94.7%)

163 (86.2%)

 Treatment to defervescence ≤3 days a

71/89 (79.8%)

38/50 (76%)

10/15 (66.7%)

119/154 (77.3%)

Underlying conditions

 Old age (≥65 years)

10 (8.7%)

12 (21.8%)

2 (10.5%)

24 (12.7%)

 Hypertension

13 (11.3%)

7 (12.7%)

1 (5.3%)

21 (11.1%)

 Diabetes mellitus

8 (7.0%)

4 (7.3%)

2 (10.5%)

14 (7.4%)

 COPD

2 (1.7%)

0 (0%)

0 (0%)

2 (1.1%)

 Cirrhosis

1 (0.9%)

4 (7.3%)

0 (0%)

5 (2.6%)

 Alcoholism

10 (8.7%)

3 (5.5%)

1 (5.3%)

14 (7.4%)

 Chronic hepatitis B

25/108 (23.1%)

6/46 (13.0%)

2 /18 (11.1%)

33/172 (19.2%)

 Chronic hepatitis C

9/108 (8.3%)

3/46 (6.5%)

1/18 (5.6%)

13/172 (7.6%)

 Chronic kidney disease

0 (0%)

0 (0%)

0 (0%)

0 (0%)

 Heart failure

2 (1.7%)

1 (1.8%)

0 (0%)

3 (1.6%)

 Old stroke

1 (0.9%)

0 (0%)

0 (0%)

1 (0.5%)

 Hematologic malignancy

1 (0.9%)

0 (0%)

0 (0%)

1 (0.5%)

 Solid tumor

1 (0.9%)

0 (0%)

0 (0%)

1 (0.5%)

 Connective tissue disease

0 (0%)

1 (1.8%)

0 (0%)

1 (0.5%)

Laboratory data (mean ± SD)

 WBC (/uL)

6153 ± 2564

7650 ± 2657

8758 ± 6837

6850 ± 3368

  Leukocytosis (WBC > 10,000/uL)

5/115 (4.3%)

10/55 (18.2%)

6/19 (31.6%)

21/189 (11.1%)

 Hemoglobin (g/dL)

14.6 ± 1.3

12.9 ± 1.7

14.0 ± 2.1

14.0 ± 1.7

  Anemia (Hb < 10 g/dL)

0/115 (0%)

3/55 (5.5%)

0/19 (0%)

3/189 (1.6%)

 Platelet (1000/uL)

139 ± 57

137 ± 69

148 ± 79

139 ± 63

  Thrombocytopenia (< 150,000/uL)

85/115 (73.9%)

39/55 (70.9%)

11/19 (57.9%)

135/189 (71.4%)

 AST (U/L)

118 ± 81

165 ± 282

162 ± 123

136 ± 169

  AST > 38 U/L

109/111 (98.2%)

47/53 (88.7%)

19/19 (100%)

175/183 (95.6%)

 ALT (U/L)

129 ± 79

149 ± 198

249 ± 440

147 ± 184

  ALT> 44 U/L

111/114 (97.4%)

42/53 (79.2%)

18/18 (100%)

171/185 (92.4%)

  1. SD standard deviation, COPD chronic obstructive pulmonary disease, TB tuberculosis, WBC white blood cell, AST aspartate transaminase, ALT alanine transaminase
  2. aPatients who received fluoroquinolones or achieved defervescence before intervention of doxycycline treatment were excluded