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Table 1 The demographic data of patients of acute Q fever, scrub typhus and, murine typhus

From: Serum C-reactive protein and procalcitonin values in acute Q fever, scrub typhus, and murine typhus

 Acute Q fever (n = 115)Scrub typhus (n = 55)Murine typhus (n = 19)Total (n = 189)
Demographics
 Male108 (93.9%)33 (60.0%)15 (78.9%)156 (82.5%)
 Age (years) (mean ± SD)44.8 ± 12.144.3 ± 16.949.8 ± 14.645.1 ± 13.9
 Admission93 (80.9%)52 (94.5%)18 (94.7%)163 (86.2%)
 Treatment to defervescence ≤3 days a71/89 (79.8%)38/50 (76%)10/15 (66.7%)119/154 (77.3%)
Underlying conditions
 Old age (≥65 years)10 (8.7%)12 (21.8%)2 (10.5%)24 (12.7%)
 Hypertension13 (11.3%)7 (12.7%)1 (5.3%)21 (11.1%)
 Diabetes mellitus8 (7.0%)4 (7.3%)2 (10.5%)14 (7.4%)
 COPD2 (1.7%)0 (0%)0 (0%)2 (1.1%)
 Cirrhosis1 (0.9%)4 (7.3%)0 (0%)5 (2.6%)
 Alcoholism10 (8.7%)3 (5.5%)1 (5.3%)14 (7.4%)
 Chronic hepatitis B25/108 (23.1%)6/46 (13.0%)2 /18 (11.1%)33/172 (19.2%)
 Chronic hepatitis C9/108 (8.3%)3/46 (6.5%)1/18 (5.6%)13/172 (7.6%)
 Chronic kidney disease0 (0%)0 (0%)0 (0%)0 (0%)
 Heart failure2 (1.7%)1 (1.8%)0 (0%)3 (1.6%)
 Old stroke1 (0.9%)0 (0%)0 (0%)1 (0.5%)
 Hematologic malignancy1 (0.9%)0 (0%)0 (0%)1 (0.5%)
 Solid tumor1 (0.9%)0 (0%)0 (0%)1 (0.5%)
 Connective tissue disease0 (0%)1 (1.8%)0 (0%)1 (0.5%)
Laboratory data (mean ± SD)
 WBC (/uL)6153 ± 25647650 ± 26578758 ± 68376850 ± 3368
  Leukocytosis (WBC > 10,000/uL)5/115 (4.3%)10/55 (18.2%)6/19 (31.6%)21/189 (11.1%)
 Hemoglobin (g/dL)14.6 ± 1.312.9 ± 1.714.0 ± 2.114.0 ± 1.7
  Anemia (Hb < 10 g/dL)0/115 (0%)3/55 (5.5%)0/19 (0%)3/189 (1.6%)
 Platelet (1000/uL)139 ± 57137 ± 69148 ± 79139 ± 63
  Thrombocytopenia (< 150,000/uL)85/115 (73.9%)39/55 (70.9%)11/19 (57.9%)135/189 (71.4%)
 AST (U/L)118 ± 81165 ± 282162 ± 123136 ± 169
  AST > 38 U/L109/111 (98.2%)47/53 (88.7%)19/19 (100%)175/183 (95.6%)
 ALT (U/L)129 ± 79149 ± 198249 ± 440147 ± 184
  ALT> 44 U/L111/114 (97.4%)42/53 (79.2%)18/18 (100%)171/185 (92.4%)
  1. SD standard deviation, COPD chronic obstructive pulmonary disease, TB tuberculosis, WBC white blood cell, AST aspartate transaminase, ALT alanine transaminase
  2. aPatients who received fluoroquinolones or achieved defervescence before intervention of doxycycline treatment were excluded