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Table 3 Schistosome count and biochemical parameters after treatment

From: Three monthly doses of 60 mg/kg praziquantel for Schistosoma haematobium infection is a safe and effective treatment regimen

Variable

Normal Range

Schistosome positive

Schistosome negative

p value

Sh count (/10 mL)

 

0

0

 

Albumin (g/L)

35–55

48.8 (45.4, 52.5)

52.9 (49.6, 55.4)

0.441

Globulin

20–35

35.8 (31.2, 39.1)

37.4 (29.7, 43.0)

0.767

Bilirubin (Direct) (μmol/L)

0–5

7.4 (5.8, 8.9)

7.0 (6.3, 8.0)

0.075

Bilirubin (Total) (μmol/L)

3–22

13.6 (11.1, 20.6)

14.2 (11.6, 16.7)

0.260

Creatinine (μmol/L)

50–110

91.0 (79.0, 111.0)

95.0 (77.0, 112.0)

0.441

GGT (U/L)

9–48

23.0 (20.0, 31.0)

26.0 (20.0, 39.0)

0.678

ALT (U/L)

5–35

11.0 (8.0, 13.0)

10.0 (9.0, 13.0)

0.513

AST (U/L)

7–40

32.0 (27.0, 35.0)

30.0 (26.0, 33.0)

0.722

AST/ALT ratio

0.8

2.8 (2.3, 3.4)

2.7 (2.1, 3.3)

0.441

Protein (g/L)

60–80

85.0 (77.0, 93.0)

85.0 (82.0, 96.0)

0.813

Urea (mmol/L)

2.9–8.2

2.5 (2.0, 2.8)

2.2 (1.9, 2.5)

0.635

eGFR (CKDEPI)

>  90

116.5 (94.0, 128.0)

94.5 (79.0, 115.0)

0.753

eGFR (4v-MDRD)

>  90

105.5 (87.0, 116.0)

90.0 (75.0, 109.0)

0.866

  1. Sh S. haematobium egg, eGFR (ml/min/1.73m2), biochemical variables, ratio and eGFR reported as median (interquartile ranges)