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Table 3 Predicting value of the baseline (T0) serum cytokines levels on active TB development among untreated controls

From: Serum level of IL-1ra was associated with the treatment of latent tuberculosis infection in a Chinese population

CytokineAUC (95%CI)p for z-testCut-off (pg/ml)Sensitivity,% (95% CI)Specificity,% (95% CI)
Eotaxin0.95 (0.87, 1.03)<0.00150.5488.89 (51.75, 99.72)94.44 (72.71, 99.86)
Basic FGF0.96 (0.88, 1.02)<0.00117.4988.89 (51.75, 99.72)94.44 (72.71, 99.86)
G-CSF0.89 (0.76, 1.02)0.00158.8988.89 (51.75, 99.72)88.89 (65.29, 98.62)
IFN-γ0.95 (0.87, 1.03)<0.00117.4188.89 (51.75, 99.72)94.44 (72.71, 99.86)
IL-1α0.92 (0.82, 1.02)0.0018.0688.89 (51.75, 99.72)88.89 (65.29, 98.62)
IL-1ra0.85 (0.70, 1.00)0.003114.70100.00 (66.37, 100.00)72.22 (46.52, 90.31)
IL-41.00 (1.00, 1.00)<0.0011.16100.00 (66.37,100.00)100.00 (81.47,100.00)
IL-80.86 (0.73, 1.00)0.0023.4477.78 (39.99, 97.19)83.33 (58.58, 96.42)
IL-90.90 (0.77, 1.04)0.00138.8588.89 (51.75, 99.72)94.44 (72.71, 99.86)
IL-17A0.80 (0.63, 0.98)<0.0013.48100.00 (66.37, 100.00)72.22 (46.52, 90.31)
MCP-1(MCAF)0.79 (0.59, 0.99)0.01610.3466.67 (29.93, 92.51)83.33 (58.58, 96.42)
MIP-1β0.75 (0.55, 0.94)0.04057.6555.56 (21.20, 86.30)94.44 (72.71, 99.86)
SDF-1α0.79 (0.61, 0.97)0.016218.00100.00 (66.37, 100.00)50.00 (26.02, 73.98)
TNF-α0.82 (0.66, 0.97)0.00910.48100.00 (66.37, 100.00)61.11 (35.75, 82.70)
TRAIL0.88 (0.74, 1.01)0.00234.5177.78 (39.99, 97.19)88.89 (65.29, 98.62)
VEGF-A0.83 (0.66, 1.00)0.00614.3188.89 (51.75, 99.72)72.22 (46.52, 90.31)
  1. Abbreviation: AUC area under curve, TB tuberculosis