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Table 1 Characteristics of the participants included in the study

From: Serum level of IL-1ra was associated with the treatment of latent tuberculosis infection in a Chinese population

 Treated participantsUntreated controls
Developed active TB during follow-upKept healthy during follow-upp valueDeveloped active TB during follow-upKept healthy during follow-upp value
Totala1224 918 
Median age (Q25-Q75) (years)69.00 (65.00, 72.50)69.00 (65.00, 73.00)0.973b67.00 (62.00, 70.00)67.00 (62.00, 70.00)0.979b
Gender, n (%)  1.000c  1.000d
 Male6 (50.00)12 (50.00) 7 (77.78)14 (77.78) 
 Female6 (50.00)12 (50.00) 2 (22.22)4 (22.22) 
Median BMI (Q25-Q75) (Kg/m2)23.54 (19.67, 26.66)24.11 (21.71, 27.25)0.535b22.46 (20.69, 23.88)25.53 (21.81, 28.00)0.029b
Fasting blood glucose, n (%)  0.253d  0.539d
 ≥7.0 mmol/L2 (16.67)1 (4.17) 0 (0.00)2 (11.11) 
 <7.0 mmol/L10 (83.33)23 (95.83) 9 (100.00)16 (88.89) 
Median INF-γrelease of QFT (Q25-Q75) (IU/ml)
 T02.47 (1.76, 5.06)2.79 (0.90, 4.81)0.651b2.06 (1.52, 2.81)1.50 (0.92, 3.29)0.520b
 T11.52 (0.91, 3.30)0.87 (0.18, 1.91)0.095b0.73 (0.63, 1.06)0.63 (0.23, 1.51)0.471b
Classified QFT results at T0 (IU/ml), n (%)
 0.35 ~ 0.700 (0.00)4 (16.67)0.279d1 (11.11)4 (22.22)0.636d
 ≥0.7012 (100.00)20 (83.33) 8 (88.89)14 (77.87) 
  1. Abbreviation: BMI body mass index, Q25 25% quantile, Q75 75% quantile, QFT QuantiFERON-TB Gold In-Tube, TB tuberculosis, T0 baseline, T1 At the end of preventive treatment. aData might not sum to total because of missing data
  2. bp for Wilcoxon rank sum test. c p for χ2 test. dp for Fisher’s exact test