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Table 4 Association between patient characteristics and time of severe manifestation

From: Prevalence and risk factors related to poor outcome of patients with severe Plasmodium vivax infection: a systematic review, meta-analysis, and analysis of case reports

Patient Characteristics Time of severe manifestation P-value*
Before treatment After treatment Before and after treatment
ARDS
 - Yes 8 (36.4) 9 (40.9) 5 (22.7) 0.002
 - No 42 (77.8) 7 (13) 5 (9.3)  
Renal failure
 - Yes 22 (78.6) 1 (3.6) 5 (17.9) 0.016
 - No 28 (58.3) 15 (31.2) 5 (10.4)  
Bleeding
 - Yes 2 (25) 2 (25) 4 (50) 0.003
 - No 48 (70.6) 14 (20.6) 6 (8.8)  
Headache
 - Yes 4 (33.3) 6 (50) 2 (16.7) 0.018
 - No 46 (71.9) 10 (15.6) 8 (12.5)  
Rash
 - Yes 4 (57.1) 0 3 (42.9) 0.032
 - No 46 (66.7) 16 (23.2) 10 (10.1)  
Urine (anuria/oliguria)
 - Yes 15 (78.9) 0 4 (21.1) 0.027
 - No 35 (61.4) 16 (28.1) 6 (10.5)  
  1. *Pearson Chi-Square