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Table 3 Association between patient characteristics and days of well response

From: Prevalence and risk factors related to poor outcome of patients with severe Plasmodium vivax infection: a systematic review, meta-analysis, and analysis of case reports

Patient Characteristics Days of well response P-value* Odd’s ratio (95%CI)
≥ 7 days < 7 days
Impaired consciousness
 - Yes 7 (17.1) 13 (59.1) 0.001 0.14 (0.04–0.46)
 - No 34 (82.9) 9 (40.9)   
Convulsion
 - Yes 0 8 (4.5) < 0.0001 3.93 (2.15–6.18)
 - No 41 (100) 14 (99.5)   
ARDS
 - Yes 19 (46.3) 3 (13.6) 0.009 5.47 (1.5–21.39)
 - No 22 (53.7) 19 (86.4)   
Renal failure
 - Yes 17 (41.5) 2 (9.1) 0.008 7.08 (1.46–34.4)
 - No 24 (58.5) 20 (90.9)   
Jaundice
 - Yes 12 (29.3) 1 (4.5) 0.021 8.69 (1.05–72.1)
 - No 29 (70.7) 21 (95.5)   
Urine (anuria/oliguria)
 - Yes 12 (29.3) 1 (4.5) 0.021 8.69 (1.05–72.1)
 - No 29 (70.7) 21 (95.5)   
Splenomegaly
 - Yes 9 (22) 12 (54.5) 0.009 0.23 (0.08–0.72)
 - No 32 (78) 10 (45.5)   
Complications during treatment
 - Yes 25 (61) 7 (31.8) 0.027 3.35 (1.12–10)
 - No 16 (39) 15 (68.2)   
  Required 2ndantimalarial drugs  
Yes No
Complications during treatment
 - Yes 11 (84.6) 23 (36.5) 0.001 9.57 (1.95–46.98)
 - No 2 (15.4) 40 (63.5)   
  1. *Pearson Chi-Square