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Table 1 Demographic characteristics of the study participants (N = 801)

From: Prevalence of Zika virus neutralizing antibodies in healthy adults in Vietnam during and after the Zika virus epidemic season: a longitudinal population-based survey

Variables

 

n

ZIKV IgM positive (%)

Crude OR (95% CI)

P-value

DENV IgG positive (%) (n = 83)

Anti-ZIKV NS1 IgG positive (%) (n = 88)

PRNT50 positive to ZIKV (%)

Age group (years)

≤15

87

11 (12.6)

1.00 (Reference)

0.05

4/11 (36.3)

3/11 (27.3)

2/87 (2.3)

16–30

295

19 (6.4)

0.48 (0.22–1.04)

9/19 (47.4)

3/21 (14.3)

3/295 (1.0)

31–45

241

31 (12.8)

1.02 (0.49–2.13)

18/31 (58.1)

7/32 (21.9)

3/241 (1.2)

46–60

127

18 (14.2)

1.14 (0.51–2.55)

14/18 (77.8)

4/18 (22.2)

1/127 (0.8)

≥60

35

3 (8.5)

0.65 (0.17–2.48)

3/3 (100)

1/5 (20)

3/35 (8.6)

NAa

16

1 (6.3)

 

1/1 (100)

1/1 (100)

1/16 (6.3)

Sex

Female

590

59 (10)

1.00 (Reference)

0.57

32/59 (54.2)

10/64 (15.6)

7/590 (1.2)

Male

211

24 (11.4)

1.15 (0.7–1.91)

17/24 (70.8)

9/24 (37.5)

6/211 (2.8)

Ethnicity

Ede

290

25 (8.6)

1.00 (Reference)

0.16

15/25 (60.0)

5/26 (19.2)

3/290 (1.0)

Kinh

503

58 (11.5)

1.42 (0.87–2.33)

34/58 (58.6)

14/62(22.6)

10/503 (2.0)

Otherb

8

0

   

0/8 (0.0)

Pregnancy

 

66

1 (1.5)

  

0/1(0.0)

0/1(0.0)

0/66 (0.0)

  1. CI confidence interval, DENV dengue virus, IgG immunoglobulin G, IgM immunoglobulin M, NA not available, OR odds ratio, ZIKV Zika virus, ssIKV NS1 IgG positive, ZIKV antibodies were determined using anti-ZIKV NS1 IgG ELISA (P/N ratio ≥ 2); PRNT50 positive to ZIKV was defined as plaque-reduction neutralization test titers with a ≥ 50% reduction in ZIKV plaque-forming units at a serum dilution of ≥1:20
  2. a Participants with missing information on age were excluded from the multivariate logistic regression analysis
  3. b Participants whose ethnicity was categorized as “Other” were combined with the “Ede” ethnic group in the multivariate logistic regression analysis