Existence of hepatitis B virus surface protein mutations and other variants: demand for hepatitis B infection control in Cambodia

Table 5 Demography and Characteristic of 42Cambodian strains with mutation in Enhancer II and Core Promoter region

No.	Isolate Name	Age class	Residence	Genotype	Length (bp)	PreS Deletion	Enhancer II and Core Promoter
No.	Isolate Name	Age class	Residence	Genotype	Length (bp)	PreS Deletion	1653	1753	1762/1764
1.	C171361m	20–29	PP	C1	3215		(+)
2.	C171360c	0–9	PP	C1	3215				(+)
3.	C174538m	20–29	PV	C1	3215		(+)		(+)
4.	C174537c	0–9	PV	C1	3215				(+)
5.	C171229m	30–39	PS	C1	3170	(+)
6.	C171228c	0–9	PS	C1	3215				(+)
7.	C174493m	40–49	KT	C1	3215
8.	C174492c	0–9	KT	C1	3215
9.	C174335m	30–39	TK	B4/C2	3215
10.	C174334c	0–9	TK	B4/C2	3215
11.	C174348m	30–39	TK	B4/C2	3215
12.	C174347c	0–9	TK	B4/C2	3215
13.	C171459	30–39	PP	C1	3194			(+)	(+)
14.	C171060	20–29	KD	C1	3215		(+)		(+)
15.	C172116	20–29	KC	C1	3215
16.	C172168	20–29	KC	C1	3191	(+)
17.	C173909	20–29	KC	C1	3215			(+)	(+)
18.	C170492	30–39	KS	C1	3215
19.	C171046	30–39	KS	C1	3215
20.	C172562	20–29	KS	B4/C2	3215
21.	C170405	40–49	KCh	B4/C2	3215			(+)
22.	C171573	40–49	KCh	C1	3215			(+)	(+)
23.	C173681	30–39	KCh	C1	3227
24.	C174314	30–39	KCh	C1	2961	(+)
25.	C173866	20–29	ST	C1	3215				(+)
26.	C171550	20–29	SR	C1	3158	(+)
27.	C174478	20–29	OM	C1	3215
28.	C173275	30–39	TA	C1	3161	(+)		(+)	(+)
29.	C171728	20–29	PS	C1	3196
30.	C172920	30–39	KT	C1	3215
31.	C173764	20–29	KT	C1	3173	(+)	(+)		(+)
32.	C173334	30–39	BT	C1	3215				(+)
33.	C172749	30–39	BT	C1	3215			(+)	(+)
34.	C171026	30–39	BT	C1	3215				(+)
35.	C173400	40–49	BT	C1	3215
36.	C170329	30–39	SRi	B2/C2	3215
37.	C174337	30–39	TK	C1	3194	(+)	(+)		(+)
38.	C170337	20–29	SRi	B4/C2	3215
39.	C171367c	0–9	PP	B4/C2	3239
40.	C172147c	0–9	RK	C1	3215
41.	C174425c	0–9	PSi	B4/C2	3215
42.	C171594c	0–9	SRi	B4/C2	3215

PP Phnom Penh, PV Preah Vihear, PSPursat, KT Kampong Thom, TK Tbong Khmum, KD Kandal, KC Kratie, KS Kampong Speu, KCh Kampong Cham, ST Stung Treng, SR Siem Reap, Sri Svay Rieng, OM Otdar Meanchey, TA Takeo, BT Battambang, RK Ratanak Kiri, PSi Preah Sihanouk, “M”: Male, “F”: Female, “C1”: hepatitis B virus subgenotype C1, “B/C”: hepatitis B virus recombinant B/C, “(+)” indicates mutation occur in the core promoter, PreC and Core regions

ISSN: 1471-2334