Mother | Child | Notes | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Isolate ID | Age class | HBsAg/ Anti-HBs | Genotype/ sub-genotype | Mutant | Isolate ID | Age | HBsAg/ Anti-HBs | Genotype/ sub-genotype | Mutant | HB-BD/ Penta | Reported Function |
C174493m | 40–49 | +/− | C1 | P127S | C174492c | 5 | +/− | C1 | P127S | −/3 | Altered hydrophilicity, electrical charge and acidity of the loop |
C171229m | 30–39 | +/− | C1 | G145R | C171228c | 5 | +/− | C1 | – | −/3 | Vaccine Escapes Mutant |
C170329 | 30–39 | +/− | B2/C2 | M133T | C170328 | 6 | −/+ | – | – | +/3 | Rescue of virion secretion |
C171039 | 30–39 | +/− | †B | M133T | C171038 | 6 | −/+ | – | – | +/3 | Rescue of virion secretion |
C171118 | 20–29 | +/− | †C | T131N, M133T | C171117 | 5 | −/− | – | – | +/3 | Rescue of virion secretion, Rescue of virion secretion |
C171550 | 20–29 | +/− | C1 | G145A | C171549 | 6 | −/+ | – | – | −/3‡ | Vaccine Escapes Mutant |
C172116 | 20–29 | +/− | C1 | P127A | C172115 | 6 | −/− | – | – | +/1‡ | Unclear |
C173073 | 30–39 | +/− | †C | I126N | C173072 | 5 | −/− | – | – | +/3 | Vaccine Escapes Mutant |
C173429 | 20–29 | +/− | †C | P127T | C173428 | 6 | −/+ | – | – | −/3‡ | Unclear |
C173706 | 30–39 | +/− | †C | P127T, G145R | C17305 | 5 | −/− | – | – | +/3‡ | Unclear, Vaccine Escapes Mutant |
C173764 | 20–29 | +/− | C1 | F134L | C173763 | 5 | −/+ | – | – | +/3 | Lower reactivity in HBsAg assay |
C173866 | 20–29 | +/− | C1 | P127T | C173865 | 6 | −/+ | – | – | NA/3‡ | Unclear |
C174337 | 30–39 | +/+ | C1 | T131P, G145R | C174336 | 6 | −/+ | – | – | +/3 | Unclear, Vaccine Escapes Mutant |
C174478 | 20–29 | +/+ | C1 | T131I | C174477 | 6 | −/+ | – | – | +/3 | Altered hydrophilicity, electrical charge and acidity of the loop |
C174483 | 20–29 | +/− | †C | I126N | C174482 | 5 | −/− | – | – | +/2 | Vaccine Escapes Mutant |
C174269 | 30–39 | +/+ | †C | I126N | C174268 | 5 | −/+ | – | – | +/3 | Vaccine Escapes Mutant |
C170464 | 30–39 | +/− | †C | T131N | C170463 | 5 | −/− | – | – | +/3 | Rescue of virion secretion |