Existence of hepatitis B virus surface protein mutations and other variants: demand for hepatitis B infection control in Cambodia

Table 2 Homology of the detected full length HBV strains isolated from 6 mother-child pairs Identity (%)

Isolate Name	C171228c	C171229m	C171360c	C171361m	C174334c	C174335m	C174347c	C174348m	C174492c	C174493m	C174537c
gC1 C171229m	99.62
gC1 C171360c	98.53	98.25
gC1 C171361m	98.35	98.25	99.78
gB4/C C174334c	91.91	92.02	91.84	91.78
gB4/C C174335m	91.94	92.05	91.87	91.81	99.9
gB4/C C174347c	91.75	91.93	91.69	91.63	98.25	98.28
gB4/C C174348m	91.78	91.96	91.72	91.66	98.28	98.32	99.96
gC1 C174492c	98.38	98.25	98.22	98.25	92.06	92.09	92.03	92.6
gC1 C174493m	98.38	98.25	98.22	98.25	92.06	92.09	92.03	92.6	100
gC1 C174537c	98.5	98.16	98.56	98.41	91.81	91.85	91.75	91.81	98.28	98.28
gC1 C174538m	98.47	98.13	98.53	98.44	91.78	91.81	91.72	91.75	98.25	98.25	99.87

The base sequence of the detected HBV strains from 6 mother-child pairs has homology from 99.62–100%
Analysis of up to 2630 bp (nt1929-nt1343) detected from the mother (C171408m) and child (C171407c) showed a 99.96% homology in the nucleotide sequence
gC1: HBV sub-genotype C1, gB4/C: recombinant HBV genotype B4/C, The isolate ID ends in “m” represents for mother and that ends in “c” represents for child

ISSN: 1471-2334