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Table 4 Factors associated with willingness to take once-daily oral pill as PrEP in the next six months (among GBMSM with experience of SDU in the past year and were not on PrEP, n = 70)

From: Uptake and willingness to use PrEP among Chinese gay, bisexual and other men who have sex with men with experience of sexualized drug use in the past year

  OR (95%CI) AOR (95%CI)
Patterns of SDU
 Poly-use of psychoactive substances during SDU the past year
  No 1.0  
  Yes 2.02 (0.58, 7.01)
 Time since the first episode of SDU
   < 1 year 1.0  
  1–2 years 1.00 (0.21, 4.77)  
  3–5 years 1.14 (0.25, 5.33)  
   > 5 years 0.59 (0.18, 1.96)
Frequency of SDU in the past year
 1 episode/month 1.0  
 1–2 episodes/month 0.81 (0.25, 2.67)  
  ≥ 3 episodes/month 1.33 (0.39, 4.58)
Condomless anal intercourse in the past year
 No 1.0  
 Yes 0.88 (0.32, 2.40)
Perceptions related to PrEP
 Positive Attitude Scale 2.30 (1.46, 3.62)*** 2.37 (1.47, 3.82)***
 Negative Attitude Scale 1.16 (0.91, 1.47)
 People who are important to you will support you to use PrEP
  Disagree/neutral 1.0 1.0
  Agree 9.14 (2.90, 28.77)*** 9.67 (2.95, 31.71)***
In general, you are confident in taking PrEP every day in the next six months
 Strongly disagree/disagree/neutral 1.0 1.0
 Agree/strongly agree 20.57 (5.75, 73.65)*** 19.68 (5.44, 71.26)***
Mental health status
 Depressive symptoms
  No clinical depressive symptoms 1.0  
  Presence of clinical depressive symptoms 0.88 (0.32, 2.40)
 Anxiety
  No/mild/anxiety 1.0  
  Severe anxiety 0.46 (0.08, 2.45)
  1. OR: crude odds ratios
  2. AOR: multivariate odds ratios obtained by multivariate logistic regression using variables in Tables 3 and 4 that were found to be statistically significant in the univariate analysis as candidates
  3. 95%CI 95% confidence interval
  4. OR, AOR and 95% were bold for variables with p < 0.05
  5. *** P < 0.001, −--: not considered in the model