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Table 4 Multivariate analysis for effect on unfavorable outcome

From: Characteristics and outcome of spontaneous bacterial meningitis in patients with diabetes mellitus

Variable Odds Ratio 95% CI P value
Septic shock 8.896 4.272–18.527 <0.001
Coagulation disorder 4.108 1.585–10.646 0.004
Age (≥65 years) 2.311 1.352–3.950 0.002
Acute renal failure 2.238 1.206–4.152 0.011
Impaired mental status 1.612 0.797–3.261 0.184
Charlson comorbidity index ≥3 1.594 0.902–2.818 0.109
Positive CSF culture 1.219 0.596–2.492 0.588
Positive blood culture 1.223 0.689–2.170 0.493
Triad of fever, neck stiffness, and change in mental status 0.801 0.443–1.450 0.464
Diabetes mellitus 0.762 0.398–1.460 0.413
White cell count in CSF > 1000/mm3 0.664 0.390–1.132 0.132
Period time 0.552 0.317–0.962 0.036
Adequate empiric antibiotic therapy 0.270 0.129–0.565 0.001
Etiology
Neisseria meningitidis 1.000 (reference)   
Streptococcus pneumoniae 1.045 0.463–2.359 0.916
Listeria monocytogenes 1.150 0.483–2.738 0.753
Gram-negative bacilli 2.893 1.043–8.027 0.041
  1. CI confidence interval. Nagelkerke’s R2 for the adjusted model = 0.446