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Table 3 Characteristics of laboratory confirmed influenza cases by virus type

From: The burden of laboratory-confirmed influenza infection in Lebanon between 2008 and 2016: a single tertiary care center experience

Characteristics

Influenza A,N = 1529

Influenza B,N = 242

Co-infection A&B,N = 55

p-value

 

n (%)

n (%)

n (%)

 

Season (N = 1826)

   

< 0.001b

Jan 2008-Jun 2008

12 (66.7)

6 (33.3)

0 (0.0)

 

2008–2009

47 (78.3)

6 (10.0)

7 (11.7)

 

2009–2010

529 (97.6)

2 (0.4)

11 (2.0)

 

2010–2011

43 (58.9)

25 (34.2)

5 (6.8)

 

2011–2012

92 (84.4)

2 (1.8)

15 (13.8)

 

2012–2013

93 (73.8)

27 (21.4)

6 (4.8)

 

2013–2014

183 (89.3)

17 (8.3)

5 (2.4)

 

2014–2015

153 (64.3)

82 (34.5)

3 (1.3)

 

2015–2016

377 (82.9)

75 (16.5)

3 (0.7)

 

Age group (N= 1826)

[0–2 years [

134 (8.8)

28 (11.6)

11 (20.0)

0.039b

[2–5 years [

205 (13.4)

25 (10.3)

9 (16.4)

 

[5–10 years [

289 (18.9)

44 (18.2)

5 (9.1)

 

[10–19 years [

283 (18.5)

37 (15.3)

7 (12.7)

 

[19–50 years [

340 (22.2)

56 (23.1)

14 (25.5)

 

[50–65 years [

138 (9.0)

25 (10.3)

1 (1.8)

 

≥ 65 years

140 (9.2)

27 (11.2)

8 (14.5)

 

Gender (N= 1826)

   

0.992

Male

764 (50.0)

121 (50.0)

27 (49.1)

 

Female

765 (50.0)

121 (50.0)

28 (50.9)

 

Underlying medical conditions (N = 1300)

Any

511 (47.8)

89 (45.2)

15 (44.1)

0.74

Cardiovascular disease

179 (16.7)

35 (17.8)

8 (23.5)

0.563

Chronic pulmonary disease

51 (4.8)

3 (1.5)

0 (0.0)

0.054

Asthma

135 (12.6)

20 (10.2)

5 (14.7)

0.543

Immunosuppressive state (other than malignancy)

16 (1.5)

3 (1.5)

0 (0.0)

1.000a

Diabetes Mellitus

81 (7.6)

13 (6.6)

2 (5.9)

0.938a

Renal disease

43 (4.0)

8 (4.1)

1 (2.9)

1.000a

Neuromuscular disorders

8 (0.7)

4 (2.0)

0 (0.0)

0.204a

Neurological disorders

47 (4.4)

8 (4.1)

3 (8.8)

0.395a

Malignancy

136 (12.7)

27 (13.7)

1 (2.9)

0.213a

Hemoglobinopathy

27 (2.5)

3 (1.5)

0 (0.0)

0.749a

Antibiotic prescription (N = 1201)

395 (40.0)

87 (47.8)

12 (37.5)

0.134

Antiviral prescription (N = 1191)

684 (69.8)

119 (65.7)

17 (56.7)

0.192

Radiologically confirmed pneumonia (N = 739)

189 (31.5)

45 (39.1)

7 (29.2)

0.260

Hospitalization rate (N = 1784)

381 (25.4)

84 (36.2)

10 (18.5)

0.001

Characteristics

Influenza A,N = 381

Influenza B,N = 84

Co-infection A&B,N = 10

p-value

n (%)

n (%)

n (%)

 

Progression of illness and in-hospital outcome

Moderate to severe disease (N = 470)

224 (59.4)

59 (71.1)

7 (70.0)

0.129a

ICU admission (N = 475)

51 (13.4)

15 (17.9)

4 (40.0)

0.042a

Oxygen therapy (N = 470)

87 (23.0)

20 (24.4)

4 (40.0)

0.399a

Mortality (N = 470)

15 (4.0)

3 (3.7)

0 (0.0)

1.000a

Hospital stay duration, mean (±SD) (N = 473)c

 

6.8 (±8.4)

6.8 (±6.7)

16.7 (±23.8)

0.02

  1. Percentages are expressed within each influenza type, except for the season variable in which percentages are expressed within each season.
  2. Pearson’s Chi-Square test was used (no expected count less than 5).
  3. Independent Sample-t test is used to compare means.
  4. a Fisher’s exact test was used when expected count was less than 5
  5. b Monte Carlo estimate was used when the data set was too large to compute exact significance
  6. c Two patients were excluded; one stayed in 113 days and the other stayed for 262 days related to their underlying medical condition (Neuromuscular disease and cerebral palsy)