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Table 2 Severity parameters of laboratory-confirmed influenza cases according to different age groups

From: The burden of laboratory-confirmed influenza infection in Lebanon between 2008 and 2016: a single tertiary care center experience

 Total n (%)[0–2[ n (%)[2–5[ n (%)[5–10[ n (%)[10–19[ n (%)[19–50[ n (%)[50–65[ n (%)≥65 n (%)p-value
Moderate to severe disease (N = 1399)591 (42.2)80 (51.9)103 (52.0)95 (45.5)60 (28.0)91 (29.3)73 (49.7)89 (53.6)< 0.001
Hospitalization rate (N = 1787)475 (26.6)57 (34.5)37 (16.2)24 (7.3)24 (7.5)103 (25.5)99 (60.4)131 (74.9)< 0.001
ICU admission (N = 1767)70 (4.0)13 (8.0)6 (2.6)1 (0.3)2 (0.6)14 (3.5)11 (6.7)23 (13.2)< 0.001
Oxygen supplementation (N = 1613)121 (7.5)13 (9.4)8 (4.1)6 (2.1)3 (1.1)17 (4.4)25 (15.5)49 (28.3)< 0.001
Mechanical ventilation (N = 1767)35 (2.0)8 (4.9)5 (2.2)1 (0.3)2 (0.6)8 (2.0)4 (2.4)7 (4.0)0.002a
Complication rate (N = 1245)295 (23.7)45 (34.4)36 (22.1)20 (11.6)16 (9.6)51 (16.9)52 (35.6)75 (45.5)< 0.001
Mortality rate in hospitalized patients (N = 469)18 (3.8)2 (3.6)2 (5.7)0 (0.0)0 (0.0)3 (2.9)5 (5.1)6 (4.6)0.909a
Duration of ICU stay in days, mean (±SD) (N = 70)9.2 (±8.9)8.2 (±5.2)8.7 (8.8)22b5.5 (±6.4)12.6 (±12.3)7.7 (±6.6)8.2 (9.3)0.533
Duration of hospital stay in days, mean (±SD) (N = 473)c7.0 (±8.8)8.5 (±10.3)8.1 (±8.7)7.2 (13.1)6.6 (±5.0)6.5 (±8.7)6.4 (±6.8)7.0 (±8.8)0.788
  1. Pearson’s Chi-Square test was used (no expected count less than 5)
  2. aFisher’s exact test was used when expected count was less than 5
  3. bOnly one patient was admitted to ICU in this age group
  4. cTwo patients were excluded; one stayed in 113 days and the other stayed for 262 days related to their underlying medical condition (Neuromuscular disease and cerebral palsy)
  5. To note that a different denominator was used to calculate the rate of each variable. The denominator depended on the number of cases with available data on the studied variable
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