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Table 4 Presence of antibiotic resistance genes (ARGs) at time points during the first year of life

From: Longitudinal assessment of antibiotic resistance gene profiles in gut microbiomes of infants at risk of eczema

  

Number of subjects#

% of subjects with ARG present at time points

Number of subjects*

% of subjects with ARG present at time points

Antibiotic resistance genotype

ARG

W3

W3 and M12

W3 and M12

W3

W3 to M3

W3 to M6

W3 to M12

W3 to M3

W3 to M6

W3 to M12

Fosfomycin

fosA

21

11

52%

8

7

6

4

88%

75%

50%

Beta-lactam

blaZ

21

2

10%

7

1

1

0

14%

14%

0%

Aminoglycoside

aac(6′)-aph(2″)

11

5

45%

5

1

0

0

20%

0%

0%

Macrolide

lsa(A)

13

2

15%

5

5

3

1

100%

60%

20%

Quinolone

oqxB

14

4

29%

5

4

1

1

80%

20%

20%

Macrolide

erm(B)

13

11

85%

4

2

2

2

50%

50%

50%

Macrolide

erm(X)

6

5

83%

4

3

2

1

75%

50%

25%

Macrolide

mef(A)

15

15

100%

4

4

3

3

100%

75%

75%

Macrolide, Lincosamide and Streptogramin B

msr(D)

14

14

100%

4

4

2

2

100%

50%

50%

Tetracycline

tet(M)

15

11

73%

4

2

1

1

50%

25%

25%

Aminoglycoside

aph(3′)-III

7

5

71%

3

2

1

1

67%

33%

33%

Sulphonamide

sul2

8

4

50%

3

3

2

2

100%

67%

67%

Tetracycline

tet(O)

6

4

67%

3

3

3

2

100%

100%

67%

Tetracycline

tet(Q)

5

4

80%

3

3

3

3

100%

100%

100%

Tetracycline

tet(W)

11

10

91%

3

3

3

3

100%

100%

100%

Beta-lactam

blaTEM-1b

9

6

67%

2

2

2

1

100%

100%

50%

Aminoglycoside

aadE

1

1

100%

1

1

0

0

100%

0%

0%

  1. # subjects with stool samples at both week 3 and month 12 (N = 22). *subjects with stool samples at all timepoints (N = 8)