Fig. 1

Clinical course of the 76-Year-Old Patient with Scrub Typhus. a shows a timeline beginning with the occurrence of the disease in 8.july.2018 and ending after his recovery in 30.sept.2018. Major events during the course of the patient’s illness are described in the line by different colours. Black means deteriorate of the disease, green means recovery of it, red means the turning point. b shows clinical laboratory examination values during the patient’s hospitalization. Blood lactic acid curve (Lac, red line), bilirubin (blue line) and procalcitonin (PCT, black line) were decreased with the treatment of doxycycline (black arrows) in 6th day, 7th day and 7th day respectively. Although platelet have been infused by iv in in 4th day, the blood platelet (PLT, green line) was still declined in 5th day. However, the blood platelet was increased obviously in 6th day own to the treatment of doxycycline and azithromycin in 5th day. c shows systemic vascular resistance index (SVRI) was increased with the treatment of doxycycline (black arrows) in 6th day, whereas it was reduced in the first 5 days. d shows the skin anabrosis on the right ear. Panel E shows the bone marrow cells are hyperplastic obviously, poisoning alteration was existed in the granulocytic cell. The megakaryocytes were obviously proliferated with maturating disorderly. Hemophagocytic phenomenon was pointed by the arrow. Panel F shows blurred shadows around the pancreas, indicated the pancreatic leakage. Besides that, the pancreatic head forms a cystic space with dense shadows, indicated the pancreatic head hematoma by CT