Fig. 8

Effects of Th17 neutralization on the subsets of DCs during P.y17XL infection. Proportion, absolute cell numbers (Column diagram, left) and representative dot plots (right) of mDCs (a, b, c) and pDCs (d, e, f) were displayed. Flow cytometric analysis was performed on spleen cells from BALB/c mice by double staining with FITC-anti-CD11c, PE-anti-CD11b and PerCP-anti-CD45R/B220. Results were presented as the arithmetic mean of 4 mice per group ± SE. Single asterisk (*) and double asterisks (**) indicated P < 0.05 and P < 0.01, respectively, compared with control mice (non-infected mice, 0d). Single pound sign (^#) and double pound sign (^##) indicates P < 0.05, and P < 0.01, respectively, between infected and Tregs depletion groups mice.* = Calculated value of ‘p’ by student’s t-test; # = Calculated value of ‘p’ by one-way ANON. P-values were calibrated using Bonferroni correction. The data are representative of three separate experiments