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Table 1 Sensitivity and specificity of diagnostic tests using gastrointestinal biopsy specimens

From: How can gastro-intestinal tuberculosis diagnosis be improved? A prospective cohort study

 

N tests

Sensitivity %

Specificity %

PPV %

NPV %

GeneXpert®

57

95.7

100

100

97.1

Culture

42

35.0

100

100

62.9

PCR

29

50.0

100

100

68.2

AFB

55

31.0

100

100

56.5

Histology a

60

68.0

77.1

68.0

77.1

Histology b

60

36.0

85.7

64.3

65.2

  1. a Histology results classified as ‘suggestive’ or ‘highly suggestive of TB’ versus results classified as not ‘suggestive of TB’ or ‘clear alternative diagnosis’
  2. b Histology results classified as ‘highly suggestive of TB’ versus results classified as ‘clear alternative diagnosis’